Evidence map›Paper›PMID 39769224›Full record

ArticleInternational journal of molecular sciences2024

Manganese(II) Complexes with Non-Steroidal Anti-Inflammatory Drugs: Structure and Biological Activity.

Filitsa Dimiza, Antonios G Hatzidimitriou, George Psomas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Filitsa DimizaDepartment of General and Inorganic Chemistry, Faculty of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
Antonios G HatzidimitriouDepartment of General and Inorganic Chemistry, Faculty of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.ORCID 0000-0001-6237-126X
George PsomasDepartment of General and Inorganic Chemistry, Faculty of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.ORCID 0000-0002-5879-7265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nine manganese(II) complexes with a series of non-steroidal anti-inflammatory drugs (namely sodium diclofenac, diflunisal, flufenamic acid, sodium meclofenamate, mefenamic acid, and tolfenamic acid) were prepared in the presence of diverse nitrogen donors, i.e., pyridine, 1,10-phenanthroline, 2,2'-bipyridine and neocuproine, as co-ligands and were characterized with spectroscopic techniques and single-crystal X-ray crystallography. The biological profile of the resultant complexes was investigated regarding their antioxidant potency and their interaction with DNA and serum albumins. The complexes interact with calf-thymus DNA in an intercalative mode and bind tightly and reversibly to human and bovine serum albumins studied. In order to assess the antioxidant activity of the Mn(II) complexes, their ability to scavenge 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) free radicals was monitored.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalCoordination ComplexesDNAManganese2,2'-DipyridylAnimalsAntioxidantsBenzothiazolesCattleCrystallography, X-RayDiclofenacDiflunisalFlufenamic AcidHumansMeclofenamic AcidMefenamic Acid1,10-phenanthroline2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid2,2'-DipyridylAnti-Inflammatory Agents, Non-SteroidalAntioxidantsBenzothiazolescalf thymus DNACoordination ComplexesDiclofenacDiflunisalDNAFlufenamic AcidManganeseMeclofenamic AcidMefenamic Acidortho-AminobenzoatesPhenanthrolinespyridinePyridinesSerum Albumin, BovineSulfonic Acidstolfenamic acidaffinity for albuminsantioxidant activityDNA interactionmanganese(II) complexesNSAIDs

Identifiers

PMID39769224
PMCPMC11676910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.