Evidence map›Paper›PMID 39769123›Full record

ArticleInternational journal of molecular sciences2024

Effect of High-Dose Vitamin C on Tendon Cell Degeneration-An In Vitro Study.

Shusuke Ueda, Toru Ichiseki, Miyako Shimasaki, Daisuke Soma, Masaru Sakurai, Ayumi Kaneuji, Norio Kawahara

Erratum issuedAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shusuke UedaDepartment of Orthopaedic Surgery, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.ORCID 0000-0003-3385-032X
Toru IchisekiDepartment of Orthopaedic Surgery, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.
Miyako ShimasakiDepartment of Pathology 2, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.
Daisuke SomaDepartment of Orthopaedic Surgery, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.
Masaru SakuraiSocial and Environmental Medicine, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.
Ayumi KaneujiDepartment of Orthopaedic Surgery, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.ORCID 0000-0001-7224-0722
Norio KawaharaDepartment of Orthopaedic Surgery, Kanazawa Medical University, Daigaku 1-1, Uchinada-machi, Kahoku-gun 920-0293, Japan.

Funding

The Ministry of Education, Culture, Sports, Science, and Technology of Japan. 19K18511
6 · The paper itself

Abstract

Tendinopathy is an aging-related disease, often caused by micro-scarring and degeneration due to overuse or trauma. Ascorbic acid (vitamin C) supplementation is reported to be a useful treatment for tendinopathy recovery. We compared the inhibitory effects of various ascorbic acid doses on tendon cell damage. H

Indexed as

Ascorbic AcidHydrogen PeroxideOxidative StressReactive Oxygen SpeciesTendonsAntioxidantsCells, CulturedCytoskeletonHumansTendinopathyAntioxidantsAscorbic AcidHydrogen PeroxideReactive Oxygen Speciesactin filamentcellular senescencehigh-dose vitamin Cmitochondrial damageoxidative injurytendon cell degeneration

Identifiers

PMID39769123
PMCPMC11678561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.