Evidence map›Paper›PMID 39769061›Full record

ArticleInternational journal of molecular sciences2024

Loss of Glutathione-S-Transferase Theta 2 (GSTT2) Modulates the Tumor Microenvironment and Response to BCG Immunotherapy in a Murine Orthotopic Model of Bladder Cancer.

Mugdha V Patwardhan, Toh Qin Kane, Edmund Chiong, Juwita Norasmara Rahmat, Ratha Mahendran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mugdha V PatwardhanDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0000-0002-0627-8156
Toh Qin KaneGenomics and Data Analytics Core, Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0001-6882-1110
Edmund ChiongDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Juwita Norasmara RahmatDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0000-0003-4134-0434
Ratha MahendranDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0000-0002-4359-2160

Funding

Joseph Lim Boon Tiong Cancer Research Initiative NA
6 · The paper itself

Abstract

Loss of the glutathione-S-transferases Theta 2 (Gstt2) expression is associated with an improved response to intravesical

Indexed as

BCG VaccineGlutathione TransferaseImmunotherapyMice, Inbred C57BLMice, KnockoutTumor MicroenvironmentUrinary Bladder NeoplasmsAnimalsB7-H1 AntigenCell Line, TumorDisease Models, AnimalFemaleGene Expression Regulation, NeoplasticHumansMiceB7-H1 AntigenBCG VaccineGlutathione TransferaseBCGbladder cancerglutathione S-transferase theta 2immunotherapyinflammationPD-L1single-cell gene expression analysisurinary bladder neoplasms

Identifiers

PMID39769061
PMCPMC11676541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.