Evidence map›Paper›PMID 39768828›Full record

ArticleMedicina (Kaunas, Lithuania)2024

Successful Treatment of Abdominal Wall Advanced Endometriosis-Associated Clear Cell Carcinoma with AKT Pathway Inhibitor: Case Report.

Ya-Ting Ko, Ching-Hsuan Wu, Cheng-Shyong Chang, De-Wei Lai, Ta-Chih Liu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ya-Ting KoDepartment of Hematology-Oncology, Chang Bing Show Chwan Memorial Hospital, Changhua 505029, Taiwan.
Ching-Hsuan WuDepartment of Hematology-Oncology, Chang Bing Show Chwan Memorial Hospital, Changhua 505029, Taiwan.
Cheng-Shyong ChangDepartment of Hematology-Oncology, Chang Bing Show Chwan Memorial Hospital, Changhua 505029, Taiwan.ORCID 0000-0003-1016-8125
De-Wei LaiDepartment of Molecular Biology and Cell Research, Chang Bing Show Chwan Memorial Hospital, Changhua 505029, Taiwan.ORCID 0000-0002-8511-380X
Ta-Chih LiuDepartment of Hematology-Oncology, Chang Bing Show Chwan Memorial Hospital, Changhua 505029, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of endometriosis-associated clear cell carcinoma (CCC) within the abdominal wall is a notably rare phenomenon. This condition predominantly impacts females who have previously undergone surgical interventions, including hysterectomy or caesarean section (C-section), with the malignant transformation of endometriosis within the post-surgical abdominal scar posited as a likely mechanism. Herein, we delineate a distinctive case of endometriosis-associated CCC emanating from the abdominal wall. The therapeutic approach for the patient encompassed surgical resection, complemented by a regimen of adjuvant chemotherapy, radiotherapy, immunotherapy, and targeted therapy. Despite these measures, the patient experienced disease progression, manifested by bilateral inguinal lymph node involvement and metastasis to the left femoral bone. Advanced molecular diagnostics, specifically next-generation sequencing (NGS) of the resected specimen, identified a targetable

Indexed as

Abdominal WallEndometriosisAdenocarcinoma, Clear CellClass I Phosphatidylinositol 3-KinasesEverolimusFemaleHumansProto-Oncogene Proteins c-aktClass I Phosphatidylinositol 3-KinasesEverolimusPIK3CA protein, humanProto-Oncogene Proteins c-aktalpelisibendometriosis-associated clear cell carcinomaeverolimusnext-generation sequencing

Identifiers

PMID39768828
PMCPMC11676099

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.