Evidence map›Paper›PMID 39768763›Full record

ReviewJournal of clinical medicine2024

Retinal Vascular Complications in Cocaine Abuse: A Case Report and a Literature Review.

Marta Armentano, Ludovico Alisi, Giacomo Visioli, Maria Carmela Saturno, Arianna Barba, Alessio Speranzini, Giuseppe Maria Albanese, Magda Gharbiya, Ludovico Iannetti

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cocaine-Induced Ocular Toxicity.Diseases (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marta ArmentanoDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Ludovico AlisiDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-5366-882X
Giacomo VisioliDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-6152-433X
Maria Carmela SaturnoDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Arianna BarbaDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.
Alessio SperanziniDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0009-0007-1574-6998
Giuseppe Maria AlbaneseDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0001-7562-9274
Magda GharbiyaDepartment of Sense Organs, Medicine and Dentistry Faculty, Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-4991-9689
Ludovico IannettiOphthalmology Unit, Head and Neck Department, Policlinico Umberto I University Hospital, 00161 Rome, Italy.ORCID 0000-0003-1790-3532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive review examines the ocular vascular complications of cocaine use, focusing on its effects on retinal vasculature and inflammation. A rare case of bilateral frosted branch angiitis (FBA) in a 48-year-old man with a history of intranasal cocaine abuse is presented as an illustrative example to stimulate discussion. The case highlights severe retinal ischemia and vascular sheathing, with no identifiable infectious or autoimmune cause, ultimately complicated by systemic vascular events. Integrating this case with a review of the literature, we discuss cocaine's vasoconstrictive and immunomodulatory effects and their role in retinal pathology, including vasculitis, vascular occlusions, hemorrhages, and optic neuropathy. Although often a diagnosis of exclusion, and with rare and poorly understood consequences, this review underscores the importance of considering cocaine abuse in the differential diagnosis of complex retinal presentations.

Indexed as

cocaine abusefrosted branch angiitisocular complicationsretinal hemorrhageretinal ischemiaretinal pathologyretinal vasculitissubstance abusevascular occlusionvitrectomy

Identifiers

PMID39768763
PMCPMC11678052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.