Evidence map›Paper›PMID 39768444›Full record

ArticleJournal of clinical medicine2024

Nociplastic Pain in Endometriosis: A Scoping Review.

Avonae Gentles, Emma Goodwin, Yomna Bedaiwy, Nisha Marshall, Paul J Yong

Abstract readScoping Review
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Review
  3. Review
  4. Review
  5. Observational
  6. Article
  7. Observational
  8. Endometriosis: An Immunologist's Perspective.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Avonae GentlesDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC V6H 3N1, Canada.ORCID 0000-0002-0457-8606
Emma GoodwinBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, BC V6H 3N1, Canada.
Yomna BedaiwyBC Women's Center for Pelvic Pain and Endometriosis, Vancouver, BC V6H 3N1, Canada.
Nisha MarshallDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC V6H 3N1, Canada.ORCID 0009-0008-7542-2490
Paul J YongDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC V6H 3N1, Canada.ORCID 0000-0001-5521-3052

Funding

CIHR PJT-156084
6 · The paper itself

Abstract

Endometriosis is an inflammatory chronic condition associated with nociceptive, neuropathic, and nociplastic pain. Central sensitization (CS) is the primary nociplastic pain mechanism. However, there are currently no standardized methods for detecting CS or nociplastic pain. This review aims to identify available tools for characterizing CS/nociplastic pain in endometriosis-related chronic pelvic pain. Following the PRISMA-P protocol, MEDLINE, Embase, Scopus, and PsychINFO databases were searched on 23 April 2024, for the terms "endometriosis", "central sensitization", "nociplastic pain", "widespread pain", and "assessment tools". Publications were selected if they mentioned tool(s) for detecting nociplastic pain or CS in endometriosis patients. Information was extracted on study demographics, assessment types, and the tools used for detection. Of the 379 citations retrieved, 30 papers met the inclusion criteria. When working to identify CS and nociplastic pain, fourteen studies exclusively used patient-reported questionnaires, six used quantitative sensory testing (QST), two used clinical assessments, and eight used multiple approaches combining patient-reported questionnaires and clinical assessment. This review illustrates the diversity of tools currently used to identify CS and nociplastic pain in endometriosis patients. Further research is needed to evaluate their validity and to standardize methods in order to improve the accuracy of nociplastic pain identification and guide treatment.

Indexed as

central sensitizationendometriosisnociplastic painpain phenotypingperipheral sensitization

Identifiers

PMID39768444
PMCPMC11727753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.