Evidence map›Paper›PMID 39768296›Full record

ArticleLife (Basel, Switzerland)2024

Evaluation of Ocular and Systemic Oxidative Stress Markers in Patients with Diabetic Retinopathy.

Ana Karen López-Contreras, Diana Esperanza Arévalo-Simental, Fermín Paúl Pacheco-Moisés, María Guadalupe Martínez-Ruíz, Cecilia Olvera-Montaño, Ricardo Raúl Robles-Rivera, Sonia Sifuentes-Franco, Tannia Isabel Campos-Bayardo, Selene Guadalupe Huerta-Olvera, Adolfo Daniel Rodríguez-Carrizalez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Karen López-ContrerasInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Diana Esperanza Arévalo-SimentalDepartment of Ophthalmology, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara 44280, Jalisco, Mexico.
Fermín Paúl Pacheco-MoisésDepartment of Chemistry, University Centre of Exact and Engineering Sciences, University of Guadalajara, Guadalajara 44430, Jalisco, Mexico.ORCID 0000-0002-3769-5649
María Guadalupe Martínez-RuízInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-8849-1208
Cecilia Olvera-MontañoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Ricardo Raúl Robles-RiveraInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Sonia Sifuentes-FrancoDepartment of Health Sciences-Disease as an Individual Process, Tonalá Campus, University of Guadalajara, Tonala 45425, Jalisco, Mexico.
Tannia Isabel Campos-BayardoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Selene Guadalupe Huerta-OlveraMedical and Life Sciences Department, La Ciénega University Center, University of Guadalajara, Ocotlan 47810, Jalisco, Mexico.ORCID 0000-0002-7160-6734
Adolfo Daniel Rodríguez-CarrizalezInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0001-9093-9406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proliferative diabetic retinopathy (PDR) is the most severe complication of chronic hyperglycaemi stimulates oxidative stress that changes the retinal basement membrane function and provokes neovascularization, macular edema and retinal detachment. But an oxidative-antioxidant biomarker assessment in ocular matrices, such as aqueous humor (AH) and vitreous, might show the oxidative stress (OS) status in the posterior segment. Here, we show a cross-sectional analytical study of 39 patients who had a vitrectomy and assess the levels of different oxidative-antioxidant biomarkers in blood, aqueous and vitreous humor in three groups: diabetes mellitus 2 (DM2) with PDR [DM(+)PDR(+)] (

Indexed as

aqueousdiabetic retinopathyoxidative stressvitreous

Identifiers

PMID39768296
PMCPMC11678300

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.