Evidence map›Paper›PMID 39768293›Full record

ArticleLife (Basel, Switzerland)2024

The Associations of Dental and Periodontal Lesions with the Microvascular Complications in Patients with Type 2 Diabetes Mellitus: A Case-Control Study.

Adina Andreea Mirea, Adela Gabriela Ștefan, Moța Maria, Diana Clenciu, Adina Mitrea, Ion Cristian Efrem, Maria Magdalena Roșu, Diana Cristina Protasiewicz-Timofticiuc, Beatrice Elena Vladu, Theodora Claudia Gheonea and 3 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Adina Andreea MireaDepartment of Oro-Dental Prevention and Oral Health, Faculty of Dentistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Adela Gabriela ȘtefanCalafat Municipal Hospital, 205200 Calafat, Romania.ORCID 0000-0003-1159-3617
Moța MariaDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Diana ClenciuDepartment of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Adina MitreaDepartment of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-5310-3033
Ion Cristian EfremDepartment of Medical Semiology, Faculty of Dentistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0001-8563-347X
Maria Magdalena RoșuDepartment of Diabetes, Nutrition and Metabolic Diseases, Faculty of Midwives and Nursing, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Diana Cristina Protasiewicz-TimofticiucDepartment of Diabetes, Nutrition and Metabolic Diseases, County Clinical Emergency Hospital of Craiova, 200642 Craiova, Romania.
Beatrice Elena VladuFaculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Theodora Claudia GheoneaDepartment of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Felicia MărășescuDepartment of Orthodontics, Faculty of Dentistry, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0009-0002-5828-7262
Moța EugenDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ionela Mihaela VladuDepartment of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0002-6133-4341

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus is closely related to periodontal disease and dental lesions, disorders which through dental infection and metabolic imbalance become negatively potentiated and cause a vicious circle that is almost impossible to break. The aim of this research was to study if the severity of dental and periodontal lesions is related to the presence of microvascular complications and glycemic control in patients with type 2 diabetes mellitus (T2DM).

methodsIn total, 112 subjects with T2DM that underwent a dental evaluation were enrolled in this case-control study. The study group included 56 patients with complicated lesions, whereas the control group included 56 patients whose gender and age matched the study group and that presented superficial lesions. The statistical analysis was carried out using SPSS 26.0, with the result being considered statistically significant if the

resultsStatistically significant differences were recorded between the two groups regarding the value of blood glucose, HbA1c and fibrinogen, as well as kidney function. Statistically significant differences were also recorded between the two groups when analyzing the presence of microvascular complications, as well as individually analyzed, in the case of diabetic peripheral sensory-motor neuropathy (

conclusionsThere is a high frequency of dental and periodontal complications in patients with T2DM. Patients with microvascular complications, elevated fasting blood glucose, and chronic inflammation, as evidenced by elevated fibrinogen, are more likely to develop complicated dental and periodontal lesions.

Indexed as

dental lesionsmicrovascular complicationsperiodontal lesionstype 2 diabetes mellitus

Identifiers

PMID39768293
PMCPMC11678667

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