Evidence map›Paper›PMID 39768288›Full record

ArticleLife (Basel, Switzerland)2024

Enhancing Amyloid PET Quantification: MRI-Guided Super-Resolution Using Latent Diffusion Models.

Jay Shah, Yiming Che, Javad Sohankar, Ji Luo, Baoxin Li, Yi Su, Teresa Wu, For The Alzheimer's Disease Neuroimaging Initiative

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jay ShahSchool of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ 85281, USA.ORCID 0000-0002-3617-2395
Yiming CheSchool of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ 85281, USA.
Javad SohankarBanner Alzheimer's Institute, Banner Health, Phoenix, AZ 85006, USA.
Ji LuoBanner Alzheimer's Institute, Banner Health, Phoenix, AZ 85006, USA.
Baoxin LiSchool of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ 85281, USA.
Yi SuBanner Alzheimer's Institute, Banner Health, Phoenix, AZ 85006, USA.ORCID 0000-0002-1946-8063
Teresa WuSchool of Computing and Augmented Intelligence, Arizona State University, Tempe, AZ 85281, USA.
For The Alzheimer's Disease Neuroimaging Initiative

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI Paul S. Aisen · 2016 to 2026
$226.7M
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI DAVID M. HOLTZMAN · 2020 to 2026
$28.7M
APOE in the Predisposition to, Protection from and Prevention of Alzheimer's DiseaseR01AG069453 · NIA · BANNER HEALTH · PI ASHTON, NICHOLAS, LANGBAUM, JESSICA BROOKE · 2020 to 2025
$27.4M
Research Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI Nicholas Ashton · 2021 to 2026
$24.9M
THE XNAT IMAGING INFORMATICS PLATFORMR01EB009352 · NIBIB · WASHINGTON UNIVERSITY · PI Daniel Scott Marcus · 2009 to 2026
$9.3M
DRIVING PERFORMANCE IN PRECLINICAL ALZHEIMER'S DISEASER01AG043434 · NIA · WASHINGTON UNIVERSITY · PI ROE, CATHERINE M · 2012 to 2016
$2.4M
Tracer harmonization for amyloid and tau PET imaging using statistical and deep learning techniquesRF1AG073424 · NIA · BANNER HEALTH · PI SU, YI · 2022 to 2022
$2.3M
Arizona Department of Health Services (ADHS) and the state of Arizona CTR057001NCATS NIH HHS UL1 TR000448NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P30 AG066444NIA NIH HHS P30 AG072980NIA NIH HHS P30AG072980NIA NIH HHS R01 AG043434NIA NIH HHS R01 AG069453NIA NIH HHS RF1 AG073424NIA NIH HHS RF1AG073424NIA NIH HHS U19 AG024904NIBIB NIH HHS R01 EB009352
6 · The paper itself

Abstract

Amyloid PET imaging plays a crucial role in the diagnosis and research of Alzheimer's disease (AD), allowing non-invasive detection of amyloid-β plaques in the brain. However, the low spatial resolution of PET scans limits the accurate quantification of amyloid deposition due to partial volume effects (PVE). In this study, we propose a novel approach to addressing PVE using a latent diffusion model for resolution recovery (LDM-RR) of PET imaging. We leverage a synthetic data generation pipeline to create high-resolution PET digital phantoms for model training. The proposed LDM-RR model incorporates a weighted combination of L

Indexed as

amyloiddeep learningdiffusion modelsmedical image super-resolutionpartial volume correction (PVC)positron emission tomography

Identifiers

PMID39768288
PMCPMC11678505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.