Evidence map›Paper›PMID 39768233›Full record

ArticleLife (Basel, Switzerland)2024

Fruit and Vegetable Consumption and Inflammatory Bowel Disease: A Case-Control Study.

Anas M Almofarreh, Haytham A Sheerah, Ahmed Arafa, Fairuz A Algori, Ghonem R Almutairi, Kafi A Alenzi, Madiha M Al-Alsehemi, Banan H Mekwar, Osama Alzeer, Haneen N Molla

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anas M AlmofarrehAssistant Deputyship for Health Investment Development, Ministry of Health, Riyadh 11451, Saudi Arabia.
Haytham A SheerahOffice of the Vice Minister of Health, Ministry of Health, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-5949-6803
Ahmed ArafaDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita 564-8565, Japan.ORCID 0000-0002-3335-2243
Fairuz A AlgoriAssistant Deputyship for Preventive Health, Ministry of Health, Riyadh 11451, Saudi Arabia.
Ghonem R AlmutairiGeneral Administration for Health Facilities Licensing, Ministry of Health, Riyadh 11451, Saudi Arabia.
Kafi A AlenziAssistant Deputyship for Medical Assistance Services, Ministry of Health, Riyadh 11451, Saudi Arabia.
Madiha M Al-AlsehemiDepartment of Legislation and Regulations, General Directorate of Nursing and Midwifery Affairs, Ministry of Health, Riyadh 11451, Saudi Arabia.ORCID 0009-0009-4950-289X
Banan H MekwarDeputyship for Therapeutic Services, Ministry of Health, Riyadh 11451, Saudi Arabia.
Osama AlzeerDepartment of Clinical Nutrition, King Khalid University Hospital, King Saud University Medical City, Riyadh 12372, Saudi Arabia.
Haneen N MollaDepartment of Clinical Nutrition, King Khalid University Hospital, King Saud University Medical City, Riyadh 12372, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic conditions with complex etiologies that may involve dietary factors. This study investigates the association between fruit and vegetable consumption and the risk of UC and CD, focusing on gender-specific differences.

methodsA hospital-based case-control study, comprising 158 UC patients (93 men and 65 women), 245 CD patients (167 men and 78 women), and 395 controls without IBD (256 men and 139 women), was conducted in Riyadh, Saudi Arabia. Fruit and vegetable consumption data were gathered through a self-administered questionnaire distributed before diagnosis. Logistic regression analysis was applied to estimate the odds ratios (ORs) and 95% confidence intervals (95% CIs) for UC and CD among the participants reporting the daily consumption of fruits and vegetables.

resultsAmong men, daily vegetable consumption was associated with higher odds of UC in the age-adjusted model [OR (95% CI): 1.78 (1.02, 3.10)], but this association became non-significant after further adjustment for body mass index, smoking, anemia, and elevated liver enzymes [OR (95% CI): 1.70 (0.91, 3.18)]. No significant associations were observed between vegetable consumption and CD. In contrast, the women who consumed vegetables every day had a non-significant inverse association with UC and a significant inverse association with CD in both the age-adjusted and multivariable-adjusted models [ORs (95% CIs): 0.44 (0.23, 0.87) and 0.41 (0.20, 0.84), respectively]. Fruit consumption was neither associated with UC nor CD in either sex.

conclusionsDaily vegetable consumption was significantly associated with decreased odds of CD among women, but not men, highlighting potential sex-specific dietary influences on IBD risk.

Indexed as

Crohn’s diseasedietfoodobservational studyulcerative colitisvegetables

Identifiers

PMID39768233
PMCPMC11678875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.