Evidence map›Paper›PMID 39768213›Full record

ArticleCells2024

Lower Plasma Lactate Concentrations After Training Support the Hypothesis of Improved Metabolic Flexibility in Male Long-Term Selected Marathon Mice Compared to Unselected Controls.

Julia Brenmoehl, Zianka Meyer, Christina Walz, Daniela Ohde, Andreas Hoeflich

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia BrenmoehlWorkgroup Endocrinology of Farm Animals, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.ORCID 0000-0002-7958-0655
Zianka MeyerWorkgroup Endocrinology of Farm Animals, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Christina WalzWorkgroup Endocrinology of Farm Animals, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Daniela OhdeWorkgroup Endocrinology of Farm Animals, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.ORCID 0000-0002-0669-8409
Andreas HoeflichWorkgroup Endocrinology of Farm Animals, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.ORCID 0000-0003-2018-2836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic flexibility describes the capability to switch between oxidative fuels depending on their availability during diet or exercise. In a previous study, we demonstrated that in response to training, marathon (DUhTP) mice, paternally selected for high treadmill performance, are metabolically more flexible than unselected control (DUC) mice. Since exercise-associated metabolic flexibility can be assessed by indirect calorimetry or partially by circulating lactate concentrations, we investigated these parameters in DUhTP and DUC mice. Therefore, males of both lines completed a three-week high-speed treadmill training or were physically inactive (sedentary) before being placed in a metabolic cage for three days (one day of acclimatization, two days with monitoring), measuring CO

Indexed as

Lactic AcidPhysical Conditioning, AnimalAnimalsFatty AcidsMaleMiceOxidation-ReductionFatty AcidsLactic Acidfat oxidation ratelactatemarathon mice DUhTPmetabolic cagesmetabolic flexibilityrespiratory quotienttreadmill training

Identifiers

PMID39768213
PMCPMC11727152

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.