Evidence map›Paper›PMID 39768198›Full record

ArticleCells2024

Anandamide Inhibits Vascular Smooth Muscle Migration, Endothelial Adhesion Protein Expression and Monocyte Adhesion of Human Coronary Artery Cells.

Elane Blessing, Elisa Teichmann, Burkhard Hinz

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elane BlessingInstitute of Pharmacology and Toxicology, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany.
Elisa TeichmannInstitute of Pharmacology and Toxicology, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany.
Burkhard HinzInstitute of Pharmacology and Toxicology, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany.ORCID 0000-0002-2529-0732

Funding

Federal Ministry of Education and Research (BMBF), Germany RESPONSE TV3 (reference: 03ZZ0933A)
6 · The paper itself

Abstract

Endocannabinoids have been shown to play a complex role in the pathophysiology of a number of cardiovascular disorders. In the present study, the effects of the two major endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG) were investigated in human coronary artery smooth muscle cells (HCASMC) and human coronary artery endothelial cells (HCAEC) with regard to potential atheroprotective and anti-inflammatory effects. In HCASMC, AEA showed an inhibitory effect on platelet-derived growth factor-induced migration, but not proliferation, independent of major cannabinoid-activatable receptors (CB

Indexed as

Arachidonic AcidsCell AdhesionCell MovementCoronary VesselsEndocannabinoidsMonocytesMuscle, Smooth, VascularPolyunsaturated AlkamidesCells, CulturedEndothelial CellsGlyceridesHumansIntercellular Adhesion Molecule-1Interleukin-1betaLipopolysaccharidesMyocytes, Smooth MuscleanandamideArachidonic AcidsEndocannabinoidsGlyceridesglyceryl 2-arachidonateIntercellular Adhesion Molecule-1Interleukin-1betaLipopolysaccharidesPolyunsaturated AlkamidesVascular Cell Adhesion Molecule-12-arachidonoylglycerolanandamideendocannabinoidendothelial cellshuman coronary arterymigrationmonocyte adhesionsmooth muscle cellsvascular cell adhesion molecule-1

Identifiers

PMID39768198
PMCPMC11727187

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.