Evidence map›Paper›PMID 39768188›Full record

ReviewCells2024

The Biomechanics of Fibrillin Microfibrils: Lessons from the Ciliary Zonule.

Pooja Rathaur, Juan Rodriguez, John Kuchtey, Samuel Insignares, Wendell B Jones, Rachel W Kuchtey, Steven Bassnett

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Ciliary Zonule of the Human Eye: Structural and Mechanical Aspects.Investigative ophthalmology & visual science · 2026
    Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pooja RathaurDepartment of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.
Juan RodriguezDepartment of Basic Sciences, University of Health Sciences and Pharmacy in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0002-6360-0770
John KuchteyVanderbilt Eye Institute, Department of Ophthalmology & Visual Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0001-5226-8648
Samuel InsignaresVanderbilt Eye Institute, Department of Ophthalmology & Visual Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0009-0003-6778-3329
Wendell B JonesDepartment of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.
Rachel W KuchteyVanderbilt Eye Institute, Department of Ophthalmology & Visual Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0003-0353-3315
Steven BassnettDepartment of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-8337-2760

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Steven Bassnett · 1985 to 2026
$18.4M
Targeting Tissue Biomechanics for Treatment of GlaucomaR01EY020894 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KUCHTEY, RACHEL W · 2010 to 2025
$6.4M
STRUCTURAL, MECHANICAL, AND CELL BIOLOGICAL PROPERTIES OF THE CILIARY ZONULER01EY029130 · NEI · WASHINGTON UNIVERSITY · PI Steven Bassnett · 2018 to 2026
$3.4M
NEI NIH HHS P30 EY002687NEI NIH HHS R01 EY020894NEI NIH HHS R01 EY029130NIH HHS P30EY002687NIH HHS R01EY020894NIH HHS R01EY029130
6 · The paper itself

Abstract

Marfan syndrome is an inherited connective tissue disorder that affects the cardiovascular, musculoskeletal, and ocular systems. It is caused by pathogenic variants in the fibrillin-1 gene (

Indexed as

MicrofibrilsAnimalsBiomechanical PhenomenaExtracellular MatrixFibrillin-1FibrillinsHumansMarfan SyndromeFibrillin-1FibrillinsfibrillinMarfan syndromemicrofibrilzonule

Identifiers

PMID39768188
PMCPMC11674075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.