ArticleChildren (Basel, Switzerland)2024
Neurocognitive Profile and Associated Factors Among Children Affected by Sickle Cell Disease in Kinshasa, Democratic Republic of Congo: A Cross-Sectional Study.
Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesUnderstanding the neurocognitive profile of children with sickle cell disease in the Democratic Republic of Congo is essential, as this condition can significantly affect their development. Our study aims to assess these children's neurocognitive and developmental profiles and identify related factors.
methodsWe conducted a descriptive cross-sectional study involving 287 children, aged 0 to 68 months, using the Mullen Scales of Early Learning and the Gensini Gavito Scale. We also screened for maternal depression using the Hopkins Symptoms Checklist-10.
resultsMore than half of the participants were boys, with an average age of 4 years. Remarkably, 95.8% (score T < x¯ +2 SD) of children scored below average on the Mullen Scales. Significant associations were found between early neurocognitive development and factors like maternal depression, socioeconomic status, maternal education, age of weaning, and responses to the Ten-Questions Questionnaire (
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