Evidence map›Paper›PMID 39767941›Full record

ArticleChildren (Basel, Switzerland)2024

Prediction of Neurodevelopmental Outcomes in Very Preterm Infants: Comparing Machine Learning Methods to Logistic Regression.

Jehier Afifi, Tahani Ahmad, Alessandro Guida, Michael John Vincer, Samuel Alan Stewart

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jehier AfifiDivision of Neonatal Perinatal Medicine, Department of Pediatrics, Dalhousie University, Halifax, NS B3K 6R8, Canada.
Tahani AhmadDepartment of Diagnostic Imaging, Dalhousie University, Halifax, NS B3K 6R8, Canada.
Alessandro GuidaDepartment of Diagnostic Imaging, Dalhousie University, Halifax, NS B3K 6R8, Canada.
Michael John VincerDivision of Neonatal Perinatal Medicine, Department of Pediatrics, Dalhousie University, Halifax, NS B3K 6R8, Canada.
Samuel Alan StewartDepartment of Community Health & Epidemiology, Dalhousie University, Halifax, NS B3H 1V7, Canada.

Funding

2021 Philips/RSNA Research seeding grant RSD2102
6 · The paper itself

Abstract

purposeIs machine learning (ML) superior to the traditionally used logistic regression (LR) in prediction of neurodevelopmental outcomes in preterm infants?

objectivesTo develop and internally validate a ML model to predict neurodevelopmental impairment (NDI) in very preterm infants (<31 weeks) at 36 months corrected age, using clinical predictors.

methodsA retrospective cohort of very preterm infants (23

resultsOf 811 eligible infants, 663 were included (mean gestational age 28 weeks, mean birth weight 1137 g and 52% male). Of those, 195 (29%) developed NDI and 468 (71%) did not. On internal validation using the testing dataset, all four models provided good discrimination of NDI with comparable AUC. RF was superior to the other three methods with a higher AUC (0.79 vs. 0.74, 0.74, and 0.73 for XGB, EN and LR, respectively), but all models have overlapped CIs.

conclusionsIn this population-based cohort of very preterm infants, RF was superior to conventional LR in prediction of NDI at 3 years corrected age. Accurate prediction of preterm infants at risk of NDI enables early referrals for intervention programs and resources allocation toward those who are most likely to benefit.

Indexed as

machine learningneurodevelopmentpredictive modelingpreterm infants

Identifiers

PMID39767941
PMCPMC11674291

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.