Evidence map›Paper›PMID 39767217›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Prognostic Utility of the Modified Systemic Inflammation Score for Patients Undergoing Oral Cavity Cancer Surgery.

Ku-Hao Fang, Sheng-Wei Lo, Adarsh Kudva, Andrea De Vito, Yuan-Hsiung Tsai, Cheng-Ming Hsu, Geng-He Chang, Ethan I Huang, Ming-Shao Tsai, Chia-Hsuan Lai and 4 more

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In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Ku-Hao FangDepartment of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.
Sheng-Wei LoDepartment of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613016, Taiwan.
Adarsh KudvaDepartment of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal 576104, India.
Andrea De VitoEar Nose Throat (ENT) Unit, Department of Surgery, Forlì Hospital Health Local Agency of Romagna, 47121 Forlì, Italy.
Yuan-Hsiung TsaiCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.
Cheng-Ming HsuCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.
Geng-He ChangCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.ORCID 0000-0001-5939-9747
Ethan I HuangCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.ORCID 0000-0002-2789-189X
Ming-Shao TsaiCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.
Chia-Hsuan LaiCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.ORCID 0000-0001-5665-743X
Ming-Hsien TsaiCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.ORCID 0000-0002-6877-1579
Chun-Ta LiaoDepartment of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.ORCID 0000-0002-3677-4249
Chung-Jan KangDepartment of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.ORCID 0000-0002-5333-9396
Yao-Te TsaiCollege of Medicine, Chang Gung University, Taoyuan 330036, Taiwan.

Funding

Chang Gung Medical Foundation grant numbers: CMRPG6N0191
6 · The paper itself

Abstract

BACKGROUND/

objectivesChronic inflammation significantly contributes to human malignancies. We investigated the prognostic significance of the preoperative modified systemic inflammation score (mSIS) in patients with primary oral cavity squamous cell carcinoma (OCSCC).

methodsWe retrospectively reviewed data from 320 OCSCC patients who underwent curative surgery between 2007 and 2017. Based on preoperative lymphocyte-to-monocyte ratio (LMR) and serum albumin levels, patients were classified into three groups: mSIS = 2 (LMR < 3.4 and albumin < 4.0 g/dL), mSIS = 1 (LMR < 3.4 or albumin < 4.0 g/dL), and mSIS = 0 (LMR ≥ 3.4 and albumin ≥ 4.0 g/dL). We explored the associations between the preoperative mSIS and overall survival (OS) and disease-free survival (DFS). We developed a nomogram based on mSIS for OS prediction.

resultsThe distribution was mSIS = 0 (

conclusionsThe mSIS reliably predicts OS and DFS in OCSCC patients undergoing surgery, with the nomogram providing individualized OS estimates, enhancing mSIS's clinical utility.

Indexed as

modified systemic inflammation scorenomogramoral cavity cancersquamous cell carcinomasurvival outcomes

Identifiers

PMID39767217
PMCPMC11674824

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