Evidence map›Paper›PMID 39767137›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Comparison of Bone Marrow Biopsy and Flow Cytometry in Demonstrating Bone Marrow Metastasis of Neuroblastoma.

Esra Arslantaş, Ali Ayçiçek, Selvinaz Özkara, Ayşe Özkan Karagenç, Sibel Akpınar Tekgündüz, Duygu Yıldırgan, Tuba Nur Tahtakesen Güçer, Ayşe Gonca Kaçar, Özgü Hançerli, Saide Ertürk and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Esra ArslantaşDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.ORCID 0000-0002-9549-5039
Ali AyçiçekDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Selvinaz ÖzkaraDepartment of Pathology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Ayşe Özkan KaragençDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Sibel Akpınar TekgündüzDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Duygu YıldırganDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Tuba Nur Tahtakesen GüçerDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Ayşe Gonca KaçarDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Özgü HançerliDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.ORCID 0000-0002-2084-402X
Saide ErtürkDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.
Ezgi Paslı UysalolDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.ORCID 0000-0001-9357-4588
Cengiz BayramDepartment of Pediatric Hematology and Oncology, Başakşehir Çam and Sakura City Hospital, Istanbul 34480, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare bone marrow aspirate (BMA) multicolor flow cytometry (MFC) analysis and bone marrow biopsy (BMB) in detecting bone marrow (BM) involvement in children with neuroblastoma (NB) at diagnosis and during follow-up. MATERIALS AND

methodsA total of 132 BM samples from 39 patients (M/F ratio: 19/20; median age: 38 months) with neuroblastoma were simultaneously obtained for evaluation. The samples were investigated for BM involvement using BMB and MFC.

resultsA comparison between MFC (

conclusionMulticolor flow cytometry may be used as an adjunct to cytomorphology to achieve more sensitive and accurate results as an objective, quantitative method with fast results in detecting bone marrow involvement in children with NB.

Indexed as

bone marrowbone marrow biopsychildrenflow cytometrymetastasisneuroblastoma

Identifiers

PMID39767137
PMCPMC11727105

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