Evidence map›Paper›PMID 39766893›Full record

ArticleGenes2024

Association Among

Shotaro Seki, Tetsuro Kobayashi, Kenji Beppu, Manabu Nojo, Kosaku Hoshina, Naoki Kikuchi, Takanobu Okamoto, Koichi Nakazato, Inkwan Hwang

Abstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shotaro SekiFaculty of Sport Science, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku 158-8508, Japan.
Tetsuro KobayashiFaculty of Sport Science, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku 158-8508, Japan.ORCID 0000-0002-2095-8254
Kenji BeppuLOGISTEED Track & Field Club House, LOGISTEED, Ltd., Hachigasakimidori-cho, Matsudo-shi 270-0024, Japan.
Manabu NojoLOGISTEED Track & Field Club House, LOGISTEED, Ltd., Hachigasakimidori-cho, Matsudo-shi 270-0024, Japan.
Kosaku HoshinaGraduate School of Media and Governance, Keio University, 5322, Endo, Fujisawa 252-0882, Japan.
Naoki KikuchiFaculty of Sport Science, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku 158-8508, Japan.ORCID 0000-0001-5901-7307
Takanobu OkamotoFaculty of Sport Science, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku 158-8508, Japan.
Koichi NakazatoFaculty of Medical Science, Nippon Sport Science University, 1221-1, Kamoshida-cho, Aoba-ku, Yokohama 227-0033, Japan.ORCID 0000-0002-2479-5771
Inkwan HwangFaculty of Sport Science, Nippon Sport Science University, 7-1-1, Fukasawa, Setagaya-ku 158-8508, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMonocarboxylate transporters (MCTs) comprise 14 known isoforms, with MCT1 being particularly important for lactate transport. Variations in lactate metabolism capacity and aerobic performance are associated with the T1470A polymorphism in

methodsWe included 158 Japanese long-distance runners (LD) and 649 individuals from the general Japanese population (CON). The frequency of the T1470A polymorphism was compared between these groups and across athletic levels using the chi-square test. Additionally, physiological data were collected from 57 long-distance runners, and respiratory gas measurements were obtained using the mixing-chamber method during a graded incremental exercise test.

resultsWe observed a significant difference between the LD and CON groups in the dominant model and between the sub-28 min group and 28 min or above group in the recessive model. As the competitive level increased, the frequency of the AA genotype also increased. When comparing physiological parameters between the AA genotype and T allele, subjects with the AA genotype showed significantly higher values for oxygen uptake at lactate threshold (

conclusionsThese results suggest that the AA genotype of the T1470A polymorphism of

Indexed as

AthletesAthletic PerformanceMonocarboxylic Acid TransportersRunningSymportersAdultEast Asian PeopleFemaleGenotypeHumansJapanLactic AcidMaleMiddle AgedMonocarboxylate Transport Protein 1Polymorphism, Single NucleotideLactic AcidMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSymportersaerobicblood lactateendurance athletesgeneticsMCT1performancepolymorphism

Identifiers

PMID39766893
PMCPMC11675177

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.