ArticleAntibiotics (Basel, Switzerland)2024
Molecular Decoration and Unconventional Double Bond Migration in Irumamycin Biosynthesis.
Vera A Alferova, Anna A Baranova, Olga A Belozerova, Evgeny L Gulyak, Andrey A Mikhaylov, Yaroslav V Solovev, Mikhail Y Zhitlov, Arseniy A Sinichich, Anton P Tyurin, Ekaterina A Trusova and 7 more
Abstract read
In one paragraphArticle in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Vera A AlferovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0002-8961-5890 Anna A BaranovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Olga A BelozerovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0002-5603-5371 Evgeny L GulyakShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0003-1272-1553 Andrey A MikhaylovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0001-9433-9141 Yaroslav V SolovevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Mikhail Y ZhitlovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0009-0007-8527-3540 Arseniy A SinichichShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0009-0001-0922-2203 Anton P TyurinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0002-5597-6161 Ekaterina A TrusovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Alexey V BeletskyInstitute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Prospect 33-2, Moscow 119071, Russia.
Andrey V MardanovInstitute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Prospect 33-2, Moscow 119071, Russia.ORCID 0000-0002-8245-8757 Nikolai V RavinInstitute of Bioengineering, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Prospect 33-2, Moscow 119071, Russia.ORCID 0000-0002-1456-1832 Olda A LapchinskayaGause Institute of New Antibiotics, B. Pirogovskaya, 11, Moscow 119021, Russia.
Vladimir A KorshunShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0001-9436-6561 Alexander G GabibovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Stanislav S TerekhovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.ORCID 0000-0003-2220-0452 Funding
Ministry of Science and Higher Education of the Russian Federation 075-15-2021-1049
6 · The paper itselfAbstract
Irumamycin (Iru) is a complex polyketide with pronounced antifungal activity produced by a type I polyketide (PKS) synthase. Iru features a unique hemiketal ring and an epoxide group, making its biosynthesis and the structural diversity of related compounds particularly intriguing. In this study, we performed a detailed analysis of the
Indexed as
antibioticbiosynthetic gene clusterepoxidationolefin shiftStreptomyces sp.type I polyketide synthase
Identifiers
PMID39766557
PMCPMC11672594
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390