Evidence map›Paper›PMID 39766513›Full record

ArticleAntibiotics (Basel, Switzerland)2024

A Nationwide Evaluation of Antibiotic Consumption in Kazakhstan from 2019 to 2023.

Yuliya Semenova, Ademi Yergaliyeva, Ainur Aimurziyeva, Almira Manatova, Anargul Kuntuganova, Larissa Makalkina, Nurgul Aldiyarova, Daniil Semenov, Lisa Lim

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Pathogens (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Social Determinants of Health and Antibiotic Consumption.Antibiotics (Basel, Switzerland) · 2025
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuliya SemenovaDepartment of Surgery, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0003-1324-7806
Ademi YergaliyevaNational Center of Public Healthcare, Astana 010000, Kazakhstan.
Ainur AimurziyevaSchool of Sciences and Humanities, Nazarbayev University, Astana 010000, Kazakhstan.
Almira ManatovaNational Scientific Center for Oncology and Transplantation, Astana 020000, Kazakhstan.
Anargul KuntuganovaDepartment of Surgery, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0002-3127-0463
Larissa MakalkinaDepartment of Clinical Pharmacology, Astana Medical University, Astana 010000, Kazakhstan.
Nurgul AldiyarovaProfessional Association of Clinical Pharmacologists and Pharmacists, Astana 010000, Kazakhstan.
Daniil SemenovComputer Science and Engineering Program, Astana IT University, Astana 010000, Kazakhstan.ORCID 0000-0003-2475-0976
Lisa LimGraduate School of Public Policy, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0009-0002-0857-9857

Funding

Nazarbayev University 211123CRP1609
6 · The paper itself

Abstract

BACKGROUND/

objectivesThere has been a lack of a holistic approach to evaluating antibiotic consumption in Kazakhstan over the past few years using an internationally recognized methodology. Therefore, this study aimed to provide a nationwide evaluation of antibiotic consumption in Kazakhstan during the period 2019-2023.

methodsDefined daily doses per 1000 inhabitants per day (DIDs) were calculated for systemic antibiotics (J01 code of the Anatomical Therapeutic Chemical Classification System (ATC)) following the methodology established by the Global Antimicrobial Resistance and Use Surveillance System (GLASS-AMC). The average annual percent change (AAPC) was computed for each chemical agent, pharmacological group, and J01 in general to evaluate past trends in antibiotic consumption.

resultsThe consumption of J01 antibiotics ranged between 10.869 DIDs (2022) and 14.470 DIDs (2020). There was an increase in antibiotic consumption during 2020 and 2021, but the overall trend was declining, with an AAPC of -2.45%. Azithromycin was the most consumed systemic antibiotic, followed by ceftriaxone and ciprofloxacin. The consumption of "Watch" group antibiotics prevailed in Kazakhstan during the study period, with the number of people consuming the top five "Watch" group antibiotics rising from 72,578 in 2019 to 94,617 in 2023.

conclusionsThe findings of this study are crucial for the reorganization of the national antimicrobial stewardship program.

Indexed as

antibiotic consumptionantimicrobial resistanceantimicrobial stewardshipdefined daily dosesKazakhstan

Identifiers

PMID39766513
PMCPMC11672648

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.