Evidence map›Paper›PMID 39766466›Full record

ReviewBrain sciences2024

Standardizing Domains and Metrics of Stroke Recovery: A Systematic Review.

Yash Akkara, Ryan Afreen, Michael Lemonick, Santiago Gomez Paz, Ziad Rifi, Jenna Tosto, David Putrino, J Mocco, Joshua Bederson, Neha Dangayach and 1 more

Abstract readReview
In one paragraph

Review in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yash AkkaraSchool of Medicine, Imperial College London, London SW7 5NH, UK.ORCID 0009-0002-5193-3639
Ryan AfreenIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0009-0005-9340-7348
Michael LemonickIcahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Santiago Gomez PazDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-2283-3612
Ziad RifiDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-3545-796X
Jenna TostoMount Sinai Health System, New York, NY 10029, USA.ORCID 0000-0002-4664-0594
David PutrinoMount Sinai Health System, New York, NY 10029, USA.
J MoccoDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Joshua BedersonDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Neha DangayachDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Christopher P KellnerDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsMeasuring stroke recovery poses a significant challenge, given the complexity of the recovery process. We aimed to identify a standardized and data-driven set of metrics of stroke rehabilitation in the literature that ensures the inclusion of all recovery domains and subdomains in the literature.

methodsA systematic review was conducted by four reviewers using the PRISMA guidelines on PubMed, MEDLINE, and Embase for stroke recovery articles between 2004 and 2024. The inclusion criteria comprised experimental/observational studies, including ischemic and hemorrhagic stroke. All studies had ≥20 participants who were ≥18 years of age, and had a follow-up of ≥3 months. Outcomes included demographics, geographic origin, stroke mechanism, domains and subdomains, metrics used, and follow-up. A bias assessment was performed using the Newcastle-Ottawa Scale and the Cochrane Risk of Bias 2.0 tool. This study was registered with PROSPERO (CRD42024551753).

resultsOur search included 324 studies with a sample of 85,156 participants. The study identified seven domains (perception, physical and motor function (PF), speech and language (S&L), cognition, activities of daily living (ADL), quality of life (QoL), and social interaction) and 96 constituent subdomains that encompass the complete landscape of the stroke recovery literature identified. The domains of PF and ADL constituted the vast share of the literature, albeit reducing in their relative representation over time, while domains such as perception and QoL have been increasingly studied since 2004. Using the domains, the study identified the set and frequency of all commonly used metrics to measure stroke recovery in the literature, of which the NIHSS (

Indexed as

domainmeasurementmetricrecoveryrehabilitationstandardstroke

Identifiers

PMID39766466
PMCPMC11674257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.