Evidence map›Paper›PMID 39766463›Full record

ArticleBrain sciences2024

Electroencephalography (EEG) for Neurological Prognostication in Post-Anoxic Coma Following Cardiac Arrest and Its Relationship to Outcome.

Zaitoon Shivji, Nathaniel Bendahan, Carter McInnis, Timothy Woodford, Michael Einspenner, Lisa Calder, Lysa Boissé Lomax, Garima Shukla, Gavin P Winston

Abstract read
In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zaitoon ShivjiEEG Department, Kingston Health Science Center, Kingston, ON K7L 2V7, Canada.
Nathaniel BendahanEdmond J. Safra Program in Parkinson's Disease, Division of Neurology, Toronto Western Hospital, University Health Network, Toronto, ON M5T 2S8, Canada.
Carter McInnisDepartment of Medicine, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Timothy WoodfordEEG Department, Kingston Health Science Center, Kingston, ON K7L 2V7, Canada.
Michael EinspennerEEG Department, Kingston Health Science Center, Kingston, ON K7L 2V7, Canada.
Lisa CalderEEG Department, Kingston Health Science Center, Kingston, ON K7L 2V7, Canada.
Lysa Boissé LomaxDepartment of Medicine, Division of Neurology, Queen's University, Kingston, ON K7L 3N6, Canada.
Garima ShuklaDepartment of Medicine, Division of Neurology, Queen's University, Kingston, ON K7L 3N6, Canada.
Gavin P WinstonDepartment of Medicine, Division of Neurology, Queen's University, Kingston, ON K7L 3N6, Canada.ORCID 0000-0001-9395-1478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesCardiac arrest may cause significant hypoxic-ischemic injury leading to coma, seizures, myoclonic jerks, or status epilepticus. Mortality is high, but accurate prognostication is challenging. A multimodal approach is employed, in which electroencephalography (EEG) forms a key part with several recognised patterns of prognostic significance.

methodsIn this retrospective study, clinical and qualitative features of the EEG of patients admitted to the Intensive Care Unit (ICU) at Kingston General Hospital following cardiac arrest from 2017 to 2020 were reviewed. The study included 81 adult patients (≥18 years). Outcome was assessed using the Cerebral Performance Category (CPC) as 1-2 (favourable) or 3-5 (unfavourable). EEG patterns were divided into groups within the highly malignant, malignant and benign patterns described in the literature.

resultsThere were a wide range of causes and 22% had a favourable outcome. Highly malignant, malignant and benign patterns were associated with survival in 0%, 70% and 100%, respectively, and favourable outcomes in 0%, 48% and 100%. All patients with seizures died, and 94% with myoclonus had unfavourable outcomes. In contrast, EEG reactivity and improvement on follow-up EEG were associated with a favourable outcome.

conclusionsHighly malignant EEG, seizures and myoclonus were associated with unfavourable outcomes, while patients with malignant EEG had better outcomes.

Indexed as

anoxic comacardiac arrestelectroencephalographyprognosis

Identifiers

PMID39766463
PMCPMC11674226

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