Evidence map›Paper›PMID 39766424›Full record

ArticleBrain sciences2024

Middle and Long Latency Cutaneous Reflexes During the Stance Phase of Gait in Individuals with and Without Chronic Ankle Instability.

Leif P Madsen, Annalee M H Friedman, Carrie L Docherty, Koichi Kitano, David M Koceja

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In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Leif P MadsenDepartment of Kinesiology, Indiana University, 1025 E 7th St, Bloomington, IN 47405, USA.
Annalee M H FriedmanDepartment of Applied Medicine and Rehabilitation, Indiana State University, 210 N 7th St, Terre Haute, IN 47809, USA.
Carrie L DochertyDepartment of Kinesiology, Indiana University, 1025 E 7th St, Bloomington, IN 47405, USA.
Koichi KitanoDepartment of Kinesiology, Indiana University, 1025 E 7th St, Bloomington, IN 47405, USA.
David M KocejaDepartment of Kinesiology, Indiana University, 1025 E 7th St, Bloomington, IN 47405, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesLower limb cutaneous reflex amplitudes can modulate across gait, which helps humans adjust rhythmic motor outputs to maintain balance in an ever-changing environment. Preliminary evidence suggests people who suffer from repetitive ankle sprains and residual feelings of giving way demonstrate altered cutaneous reflex patterns in the gastrocnemius. However, before cutaneous reflex assessment can be implemented as a clinical outcome measure, there is a need to substantiate these early findings by measuring reflex amplitudes across longer latency periods and exploring the variability of reflexes within each subject.

methodsForty-eight subjects with and without chronic ankle instability (CAI) walked on a treadmill at 4 km/h while activity of the lateral gastrocnemius (LG) was measured via surface electromyography. Non-noxious stimulations were elicited randomly to the ipsilateral sural nerve at the mid-stance phase of gait, and reflex amplitudes were calculated offline by comparing muscle activity during unstimulated and stimulated gait cycles. Two primary outcome measures were compared between groups at the middle latency (MLR: 80-120 ms) and late latency (LLR: 120-150 ms) time windows: (1) average reflex amplitudes and (2) standard deviation of reflex amplitudes for each subject across 10 trials.

resultsBoth groups demonstrated an equal amount of LG inhibition at the MLR and LG facilitation at the LLR. However, subjects with CAI showed significantly higher variability in LLR amplitude across trials than healthy controls.

conclusionsIncreased variability of cutaneous reflex amplitudes may relate to symptoms associated with CAI. These findings suggest that reflex variability following sural nerve stimulation could serve as an objective measure to track treatment progress in patients with CAI, offering clinicians a new tool for conducting rehabilitation assessments in a controlled environment.

Indexed as

ankle instabilitycutaneous reflexesgait

Identifiers

PMID39766424
PMCPMC11727029

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