Evidence map›Paper›PMID 39766178›Full record

ArticleCancers2024

Effectiveness of the Korean National Cancer Screening Program in Reducing Colorectal Cancer Mortality.

Hyeon Ji Lee, Kyeongmin Lee, Byung Chang Kim, Jae Kwan Jun, Kui Son Choi, Mina Suh

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Current Status of the National Cancer Screening Program in Korea: History, Achievements, and Future Directions.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyeon Ji LeeNational Cancer Control Institute, National Cancer Center, Goyang 10408, Republic of Korea.
Kyeongmin LeeDepartment of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Republic of Korea.ORCID 0000-0002-2629-6669
Byung Chang KimCenter for Colorectal Cancer, Center for Cancer Prevention and Detection, National Cancer Center, Goyang 10408, Republic of Korea.ORCID 0000-0003-3164-5824
Jae Kwan JunNational Cancer Control Institute, National Cancer Center, Goyang 10408, Republic of Korea.ORCID 0000-0003-1647-0675
Kui Son ChoiNational Cancer Control Institute, National Cancer Center, Goyang 10408, Republic of Korea.ORCID 0000-0001-5336-3874
Mina SuhNational Cancer Control Institute, National Cancer Center, Goyang 10408, Republic of Korea.ORCID 0000-0001-8101-7493

Funding

National Cancer Center 2210850-3
6 · The paper itself

Abstract

backgroundWhether colorectal cancer (CRC) screening with a fecal immunochemical test (FIT) reduces mortality remains unclear. In South Korea, CRC screening with a FIT for individuals aged ≥ 50 years has been part of the Korean National Cancer Screening Program (KNCSP) since 2004. The aim of this study was to evaluate the effectiveness of the KNCSP in reducing CRC-specific mortality.

methodsWe conducted a nested case-control study using cohort-based data derived from the KNCSP database. The cohort included 5,944,540 colorectal cancer-free individuals aged ≥ 50 years as of 2004. Individuals who died after CRC diagnosis were defined as cases (

resultsCompared with individuals who had never been screened, those who had ever been screened showed an OR of 0.74 (95% CI, 0.71-0.76) for CRC-specific mortality. CRC-specific mortality decreased as the number of screenings increased. Similar results were observed for those aged 50-79 years; however, the results for those aged 75-79 years were not statistically significant. Moreover, those aged ≥ 80 years had the opposite results.

conclusionsCRC mass screening using FIT is effective for individuals aged 50-74 years; therefore, this study suggests that countries considering introducing national CRC screening implement FIT for those within this age range.

Indexed as

cause of deathcolorectal neoplasmsearly detection of cancerfecal immunochemical testmass screening

Identifiers

PMID39766178
PMCPMC11674503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.