Evidence map›Paper›PMID 39766123›Full record

ReviewCancers2024

The Intersection of Psoriasis and Neoplasia: Risk Factors, Therapeutic Approaches, and Management Strategies.

Larisa-Alexandra Mateescu, Alexandra-Petruța Savu, Costina-Cristiana Mutu, Cezara-Diana Vaida, Elena-Daniela Șerban, Ștefana Bucur, Elena Poenaru, Alin-Codruț Nicolescu, Maria-Magdalena Constantin

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Larisa-Alexandra Mateescu2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Alexandra-Petruța Savu2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.ORCID 0000-0002-5964-7699
Costina-Cristiana Mutu2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Cezara-Diana Vaida2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Elena-Daniela Șerban2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.ORCID 0000-0002-2600-614X
Ștefana Bucur2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.
Elena PoenaruFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-6414-0841
Alin-Codruț NicolescuFaculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-4828-464X
Maria-Magdalena Constantin2nd Department of Dermatology, Colentina Clinical Hospital, 020125 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between psoriasis and increased cancer risk is gaining recognition as studies reveal shared inflammatory and immune pathways. This review examines the relationship between psoriasis and neoplasia, focusing on cancer risk factors in psoriasis patients, the biological pathways underlying this connection, and the impact of various psoriasis treatments on cancer development. Psoriasis patients have a heightened incidence of certain cancers, such as lymphomas, skin cancers, and urological malignancies, potentially linked to immune dysregulation and chronic inflammation. Immunomodulatory treatments for psoriasis, including conventional systemic therapies and biologics, present varied cancer risks, with others, such as phototherapy, associated with an elevated risk of skin cancers. For oncologic patients with psoriasis, management necessitates a tailored approach, balancing effective psoriasis control with minimizing cancer progression risks. The emergence of IL-17 inhibitors, IL-23 inhibitors, and small-molecule therapies offers promising therapeutic alternatives with favorable safety profiles for these patients. This review underscores the need for interdisciplinary collaboration to optimize care for patients managing both psoriasis and malignancy.

Indexed as

cancerneoplasiapsoriasistreatment

Identifiers

PMID39766123
PMCPMC11674284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.