Evidence map›Paper›PMID 39766096›Full record

ArticleCancers2024

Intracystic Glucose Measurement for On-Site Differentiation Between Mucinous and Non-Mucinous Pancreatic Cystic Lesions.

Angelo Bruni, Leonardo Henry Eusebi, Andrea Lisotti, Claudio Ricci, Marcello Maida, Pietro Fusaroli, Giovanni Barbara, Riadh Sadik, Nico Pagano, Per Hedenström and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Angelo BruniIRCCS Azienda Ospedaliero Universitaria di Bologna, Policlinico S. Orsola, 40138 Bologna, Italy.ORCID 0009-0002-0895-1225
Leonardo Henry EusebiIRCCS Azienda Ospedaliero Universitaria di Bologna, Policlinico S. Orsola, 40138 Bologna, Italy.ORCID 0000-0003-3323-7744
Andrea LisottiGastroenterology Unit, Hospital of Imola, University of Bologna, 40138 Bologna, Italy.
Claudio RicciIRCCS Azienda Ospedaliero Universitaria di Bologna, Policlinico S. Orsola, 40138 Bologna, Italy.
Marcello MaidaDepartment of Medicine and Surgery, University of Enna 'Kore', 94100 Enna, Italy.ORCID 0000-0002-4992-9289
Pietro FusaroliGastroenterology Unit, Hospital of Imola, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-4397-9314
Giovanni BarbaraIRCCS Azienda Ospedaliero Universitaria di Bologna, Policlinico S. Orsola, 40138 Bologna, Italy.
Riadh SadikDepartment of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg University, 413 45 Gothenburg, Sweden.
Nico PaganoGastroenterology Unit, Department of Oncological and Specialty Medicine, University Hospital Maggiore della Carità, 28100 Novara, Italy.
Per HedenströmDepartment of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg University, 413 45 Gothenburg, Sweden.ORCID 0000-0002-4106-1454
Giovanni MarascoIRCCS Azienda Ospedaliero Universitaria di Bologna, Policlinico S. Orsola, 40138 Bologna, Italy.ORCID 0000-0001-7167-8773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic cystic lesions (PCLs) are frequently detected incidentally and vary from benign to malignant. Accurate differentiation between mucinous (M-PCLs) and non-mucinous PCLs (NM-PCLs) is essential for appropriate management. This study aims to validate the accuracy of on-site glucose measurement using a glucometer with a cut-off of 50 mg/dL for distinguishing M-PCLs from NM-PCLs.

methodsIn this prospective multicenter study, conducted at three European academic hospitals, patients who underwent endoscopic ultrasound-guided fine-needle aspiration for PCLs between 2019 and 2020 were included. On-site glucose measurement was performed using a conventional glucometer. Data on demographics, clinical features, EUS findings, and histopathology were collected.

resultsFifty patients were enrolled, with 37 having glucose levels < 50 mg/dL and 13 ≥ 50 mg/dL. M-PCLs were more common in the <50 mg/dL group (81%) compared to the ≥50 mg/dL group (23%,

conclusionsOn-site glucose measurement using a glucometer with a cut-off of <50 mg/dL is a highly accurate, rapid, and cost-effective method for differentiating M-PCLs from NM-PCLs. Our results validate the glucose cut-off in a multicentric prospective cohort supporting its integration into standard diagnostic protocols for PCLs.

Indexed as

CEAEUS–FNAglucosemucinous cystpancreatic cyst

Identifiers

PMID39766096
PMCPMC11674768

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.