Evidence map›Paper›PMID 39765960›Full record

ArticleHealthcare (Basel, Switzerland)2024

Association of Systemic Inflammation with Dietary Intake, Nutrition Impact Symptoms, and Eating-Related Distress Among Patients with Advanced Cancer.

Koji Amano, Saori Koshimoto, Satomi Okamura, Tatsuma Sakaguchi, Sayaka Arakawa, Yoshinobu Matsuda, Akihiro Tokoro, Takashi Takeuchi, Eriko Satomi, Tamiki Wada and 3 more

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The multidimensional impact of malnutrition in incurable cancer.Current opinion in supportive and palliative care · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Koji AmanoDepartment of Supportive and Palliative Care, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka 541-8567, Japan.ORCID 0000-0002-1779-6389
Saori KoshimotoLiaison Psychiatry and Psycho-Oncology Unit, Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
Satomi OkamuraDepartment of Medical Innovation, Osaka University Hospital, 2-2 Yamadaoka, Suita 565-0871, Japan.ORCID 0000-0002-8368-0640
Tatsuma SakaguchiDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute 480-1195, Japan.ORCID 0000-0002-2246-9526
Sayaka ArakawaDepartment of Palliative Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Yoshinobu MatsudaDepartment of Psychosomatic Internal Medicine and Supportive and Palliative Care Team, NHO Kinki Chuo Chest Medical Center, 1180 Nagasone-cho, Kita-ku, Sakai 591-8555, Japan.ORCID 0000-0001-5092-9377
Akihiro TokoroDepartment of Psychosomatic Internal Medicine and Supportive and Palliative Care Team, NHO Kinki Chuo Chest Medical Center, 1180 Nagasone-cho, Kita-ku, Sakai 591-8555, Japan.
Takashi TakeuchiLiaison Psychiatry and Psycho-Oncology Unit, Department of Psychiatry and Behavioral Sciences, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
Eriko SatomiDepartment of Palliative Medicine, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.ORCID 0000-0003-1516-2849
Tamiki WadaDepartment of Psychiatry, Osaka University Graduate School of Medicine, D3 2-2 Yamadaoka, Suita 565-0871, Japan.
Makoto WadaDepartment of Psycho-Oncology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka 541-8567, Japan.
Tomomi YamadaDepartment of Medical Innovation, Osaka University Hospital, 2-2 Yamadaoka, Suita 565-0871, Japan.ORCID 0000-0002-5855-8897
Naoharu MoriDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, 1-1 Yazakokarimata, Nagakute 480-1195, Japan.

Funding

JSPS KAKENHI 22K11839JSPS KAKENHI 23K10970Project Mirai Cancer Research Grants NA
6 · The paper itself

Abstract

backgroundSerum C-reactive protein (CRP) levels are correlated with patient outcomes in cancer. This study aimed to determine associations between the CRP level and the dietary intake, symptoms, and eating-related distress (ERD).

methodsWe conducted a multicenter survey among advanced cancer patients. Information on patient characteristics was retrieved from the electronic medical records. Data on patient outcomes were obtained through the questionnaire. Patients were categorized into the low CRP group (<5 mg/dL) and the high CRP group (≥5 mg/dL). Comparisons were calculated using the Mann-Whitney U test or chi-squared test. To assess associations between CRP levels and ERD, multivariate logistic regression analysis was performed.

resultsA total of 191 patients were enrolled and divided into the low CRP group (

conclusionsHigh CRP levels were significantly associated with reduced dietary intake, appetite loss, and ERD. A serum CRP value of 5 mg/dL may be a useful indicator for initiating cancer cachexia care.

Indexed as

cachexiacancerC-reactive proteindistressquality of lifesymptomsystemic inflammation

Identifiers

PMID39765960
PMCPMC11675562

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.