Evidence map›Paper›PMID 39765944›Full record

ReviewHealthcare (Basel, Switzerland)2024

A Systematic Review of Virtual Reality's Impact on Anxiety During Palliative Care.

Alexandra-Maria Gaina, Cristinel Stefanescu, Andreea-Silvana Szalontay, Marcel-Alexandru Gaina, Vladimir Poroch, Daniela Viorica Mosoiu, Bogdan-Victor Stefanescu, Magdalena Axinte, Cristina-Maria Tofan, Liviu Adrian Magurianu

Registry-linked trialAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07567391 (Virtual Reality Nature Therapy for Palliative Patients and Caregivers in Saudi Arabia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07567391 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Virtual Reality Nature Therapy for Palliative Patients and Caregivers in Saudi Arabia: A Randomized Controlled Trial to Support Quality of Life and Cultural Adaptation

TypeinterventionalSponsorUniversity of BishaRan2026 to 2027Enrolled100ConditionsVirtual Reality, Quality of Life, Palliative Care, CaregiversArmsImmersive Nature VR
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra-Maria GainaDepartment of Medicine III, Faculty of Medicine"Grigore T. Popa", University of Medicine and Pharmacy of Iasi, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0009-0004-8374-4255
Cristinel StefanescuDepartment of Medicine III, Faculty of Medicine"Grigore T. Popa", University of Medicine and Pharmacy of Iasi, 16 Universitatii Street, 700115 Iasi, Romania.
Andreea-Silvana SzalontayDepartment of Medicine III, Faculty of Medicine"Grigore T. Popa", University of Medicine and Pharmacy of Iasi, 16 Universitatii Street, 700115 Iasi, Romania.
Marcel-Alexandru GainaDepartment of Medicine III, Faculty of Medicine"Grigore T. Popa", University of Medicine and Pharmacy of Iasi, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0003-0533-9014
Vladimir PorochDepartment of Medicine III, Faculty of Medicine"Grigore T. Popa", University of Medicine and Pharmacy of Iasi, 16 Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0002-2503-5395
Daniela Viorica MosoiuRomanian National Palliative Care Association, "Grigore T. Popa" University of Medicine and Pharmacy, Main Building A1, 16 Universitatii Street, 700115 Iasi, Romania.
Bogdan-Victor StefanescuDepartment of Medicine III, Faculty of Medicine"Grigore T. Popa", University of Medicine and Pharmacy of Iasi, 16 Universitatii Street, 700115 Iasi, Romania.
Magdalena AxinteRomanian Academy, Carol I Boulevard 8, 700506 Iași, Romania.
Cristina-Maria TofanRomanian Academy, Carol I Boulevard 8, 700506 Iași, Romania.ORCID 0000-0002-8733-725X
Liviu Adrian MagurianuRomanian Academy, Carol I Boulevard 8, 700506 Iași, Romania.

Funding

Grigore T Popa University of Medicine and Pharmacy PhD ScholarshipRomanian Academy GAR 56
6 · The paper itself

Abstract

backgroundVirtual Reality (VR) is an emerging non-pharmacological treatment for anxiety in palliative care patients. Anxiety, a common symptom in this population, has a significant effect on living standards. The aim of this systematic review is to evaluate the effectiveness of VR interventions in reducing anxiety and improving quality of life in palliative care.

methodsThe systematic review protocol was registered in PROSPERO (CRD42024517914). The comprehensive search was performed in nine databases, including PubMed, PsycINFO, and EMBASE, and included studies published up to 15 November 2024. RCTs, pilot studies, and feasibility trials involving adult palliative care patients in which VR interventions were used, were compared with standard care. Two reviewers independently extracted and assessed the quality of the data using the RoB 2 tool.

resultsA total of 13 studies were considered eligible, with 333 participants aged 15 to 85 years old. In these experiments, anxiety decreased steadily, and in some cases mood and quality of life were improved significantly. The VR interventions ranged from guided nature walks to memory-training sessions. Sessions lasted between 5 and 30 min and ranged in duration from single sessions to daily use. Personalized and participatory VR-based content was particularly effective in alleviating anxiety. The heterogeneity of the study designs and VR protocols hampered meta-analysis, despite promising findings.

conclusionsVR has considerable potential as an adjunctive anxiety therapy for palliative care. The personalization and immersion that VR provides are psychologically unique and have the potential to lower anxiety and improve well-being. But standardizing intervention protocols and more studies are required to define the best VR strategies and evaluate outcomes over the long term. The article highlights the promise of VR as part of palliative care as a viable bio-psycho-socio-spiritual approach.

Indexed as

anxiety managementnon-pharmacological treatmentspalliative carequality of lifesystematic reviewvirtual reality

Identifiers

PMID39765944
PMCPMC11728091

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.