Evidence map›Paper›PMID 39765915›Full record

ArticleAntioxidants (Basel, Switzerland)2024

From Spent Black and Green Tea to Potential Health Boosters: Optimization of Polyphenol Extraction and Assessment of Their Antioxidant and Antibacterial Activities.

Ahlam Harfoush, Aseel Swaidan, Salma Khazaal, Elie Salem Sokhn, Nabil Grimi, Espérance Debs, Nicolas Louka, Nada El Darra

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Valorization of Hazelnut (Antioxidants (Basel, Switzerland) · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahlam HarfoushDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Tarik El Jedidah, Riad El Solh, P.O. Box 115020, Beirut 1107 2809, Lebanon.
Aseel SwaidanDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Tarik El Jedidah, Riad El Solh, P.O. Box 115020, Beirut 1107 2809, Lebanon.
Salma KhazaalDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Tarik El Jedidah, Riad El Solh, P.O. Box 115020, Beirut 1107 2809, Lebanon.
Elie Salem SokhnDepartment of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut 1107 2809, Lebanon.ORCID 0000-0003-1519-6790
Nabil GrimiCentre de Recherche Royallieu-CS 60319, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Université de Technologie de Compiègne, 60203 Compiègne CEDEX, France.ORCID 0000-0002-7804-0438
Espérance DebsDepartment of Biology, Faculty of Arts and Sciences, University of Balamand, P.O. Box 100, Tripoli 1300, Lebanon.ORCID 0000-0003-1637-7518
Nicolas LoukaUnité de Recherche Technologies et Valorisation Agro-Alimentaire, Centre d'Analyses et de Recherche, Faculté des Sciences, Université Saint-Joseph de Beyrouth, Mar Roukos-Dekwaneh, Riad El Solh, P.O. Box 1514, Beirut 1107 2050, Lebanon.ORCID 0000-0001-5645-5926
Nada El DarraDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Tarik El Jedidah, Riad El Solh, P.O. Box 115020, Beirut 1107 2809, Lebanon.ORCID 0000-0002-6568-5536

Funding

the Arab-German Young Academy of Sciences and Humanities (AGYA) AGYA is funded by the German Federal Ministry of Education and Research (BMBF) grant 01DL20003.
6 · The paper itself

Abstract

Tea, one of the most popular beverages worldwide, generates a substantial amount of spent leaves, often directly discarded although they may still contain valuable compounds. This study aims to optimize the extraction of polyphenols from spent black tea (SBT) and spent green tea (SGT) leaves while also exploring their antioxidant and antibacterial properties. Response surface methodology was utilized to determine the optimal experimental conditions for extracting polyphenols from SBT and SGT. The total phenolic content (TPC) was quantified using the Folin-Ciocalteu method, while antioxidant activity was evaluated through the DPPH assay. Antibacterial activity was assessed using the disk diffusion method. Additionally, high-performance liquid chromatography (HPLC) was employed to analyze the phytochemical profiles of the SBT and SGT extracts. Optimal extraction for SBT achieved 404 mg GAE/g DM TPC and 51.5% DPPH inhibition at 93.64 °C, 79.9 min, and 59.4% ethanol-water. For SGT, conditions of 93.63 °C, 81.7 min, and 53.2% ethanol-water yielded 452 mg GAE/g DM TPC and 78.3% DPPH inhibition. Both tea extracts exhibited antibacterial activity against Gram-positive bacteria, with SGT showing greater efficacy against

Indexed as

antibacterialantioxidantpolyphenolsspent black teaspent green teawaste management

Identifiers

PMID39765915
PMCPMC11673901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.