Evidence map›Paper›PMID 39765844›Full record

ReviewAntioxidants (Basel, Switzerland)2024

Lipid Nanovesicles for Antioxidant Delivery in Skin: Liposomes, Ufasomes, Ethosomes, and Niosomes.

Agnese Ricci, Luca Stefanuto, Tecla Gasperi, Fabio Bruni, Daniela Tofani

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agnese RicciDepartment of Science, Section of Nanoscience and Nanotechnologies, "Roma Tre" University, Via della Vasca Navale 79, 00146 Rome, Italy.ORCID 0000-0001-7441-8037
Luca StefanutoDepartment of Science, Section of Nanoscience and Nanotechnologies, "Roma Tre" University, Via della Vasca Navale 79, 00146 Rome, Italy.ORCID 0000-0003-0158-5285
Tecla GasperiDepartment of Science, Section of Nanoscience and Nanotechnologies, "Roma Tre" University, Via della Vasca Navale 79, 00146 Rome, Italy.ORCID 0000-0003-3638-2517
Fabio BruniDepartment of Science, Section of Nanoscience and Nanotechnologies, "Roma Tre" University, Via della Vasca Navale 84, 00146 Rome, Italy.ORCID 0000-0002-2290-0283
Daniela TofaniDepartment of Science, Section of Nanoscience and Nanotechnologies, "Roma Tre" University, Via della Vasca Navale 79, 00146 Rome, Italy.ORCID 0000-0003-1028-9832

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin, being the largest organ of the human body, serves as the primary barrier against external insults, including UV radiation, pollutants, and microbial pathogens. However, prolonged exposure to these environmental stressors can lead to the generation of reactive oxygen species (ROS), causing oxidative stress, inflammation, and ultimately, skin aging and diseases. Antioxidants play a crucial role in neutralizing ROS and preserving skin health by preventing oxidative damage. In recent years, nanotechnology has emerged as a powerful tool for enhancing the delivery of antioxidants onto the skin. In particular, liposomal formulations have offered unique advantages such as improved stability, controlled release, and enhanced penetration through the skin barrier. This has led to a surge in research focused on developing liposomal-based antioxidant delivery systems tailored for skin health applications. Through a comprehensive analysis of the literature from the 2019-2024 period, this review provides an overview of emerging trends in the use of liposomal delivery systems developed for antioxidants aimed at improving skin health. It explores the latest advancements in liposomal formulation strategies, vesicle characterization, and their applications in delivering antioxidants to combat oxidative stress-induced skin damage and other associated skin pathologies. A comparison of various delivery systems is conducted for the most common antioxidants. Finally, a brief analysis of lipid nanovesicles used in the cosmeceutical industry is provided.

Indexed as

antioxidantsdelivery systemsethosomesliposomesniosomes

Identifiers

PMID39765844
PMCPMC11727561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.