Evidence map›Paper›PMID 39765773›Full record

ReviewAntioxidants (Basel, Switzerland)2024

MnSOD Mimetics in Therapy: Exploring Their Role in Combating Oxidative Stress-Related Diseases.

Jovan Grujicic, Antiño R Allen

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jovan GrujicicDivision of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0009-0009-8310-2945
Antiño R AllenDivision of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0002-4294-6473

Funding

NIH HHS 1R01CA258673
6 · The paper itself

Abstract

Reactive oxygen species (ROS) are double-edged swords in biological systems-they are essential for normal cellular functions but can cause damage when accumulated due to oxidative stress. Manganese superoxide dismutase (MnSOD), located in the mitochondrial matrix, is a key enzyme that neutralizes superoxide radicals (O

Indexed as

mangafodipirmanganese superoxide dismutase (MnSOD)mitochondria-targeted antioxidantsMitoQ10Mn porphyrinsMn salensMnSOD mimeticsnitroxidesoxidative stressreactive oxygen species (ROS)

Identifiers

PMID39765773
PMCPMC11672822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.