ReviewBiology2024
Pregametogenesis: The Earliest Stages of Gonad and Germline Differentiation in Anuran Amphibians.
Review in Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- Sex-Specific Gene Expression Ontogeny During Gonadal Development in Post-Metamorphic Xenopus tropicalis.Molecular reproduction and development · 2026Article
- Investigating Sexual Characteristics in Two Frog Species Under Exposure to River Water Polluted with Endocrine Disruptors.Animals : an open access journal from MDPI · 2025Article
- Early female germline development inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Clonal analysis reveals differential PGC contributions to the early germline and ovarian reserve.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gonads of amphibians, like other vertebrates, consist of somatic tissues, which create a specific environment essential for the differentiation of germline cells. The earliest stages of gametogenesis still remain underexplored in anuran amphibians. We propose to introduce the term "pregametogenesis" for a specific period of gonocyte proliferation and differentiation that occurs exclusively during the early stages of gonadal development. This review shows the key steps of early gonad differentiation in anuran amphibians and further compares chromatin reorganization in gonocytes of mammals and hybridogenetic water frogs. In mammals, this phase involves resetting genomic imprinting, which is crucial for determining gene expression in offspring. In hybridogenetic
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.