Evidence map›Paper›PMID 39765280›Full record

ArticleThe journal of pain2025

Ecological momentary assessment of cigarette smoking behavior and pain intensity among individuals with chronic back pain who smoke.

Dana Rubenstein, Michael J Green, Francis J Keefe, F Joseph McClernon, Maggie M Sweitzer

Abstract read
In one paragraph

Article in The journal of pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Integrating Pain Assessment in Nicotine and Tobacco Research and Treatment to Improve Cessation Outcomes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dana RubensteinDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2400 Pratt Street, Durham, NC 27705, United States; Clinical and Translational Science Institute, Duke University School of Medicine,Chesterfield Building, 701 W. Main St., Durham, NC 27701, United States. Electronic address: dana.rubenstein@duke.edu.
Michael J GreenDepartment of Obstetrics and Gynecology, Duke University School of Medicine, Duke University Medical Center 3084,203 Baker House, Durham, NC 27710, United States.
Francis J KeefeDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2400 Pratt Street, Durham, NC 27705, United States.
F Joseph McClernonDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2400 Pratt Street, Durham, NC 27705, United States; Clinical and Translational Science Institute, Duke University School of Medicine,Chesterfield Building, 701 W. Main St., Durham, NC 27701, United States.
Maggie M SweitzerDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2400 Pratt Street, Durham, NC 27705, United States.

Funding

NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
Using Very Low Nicotine Content Cigarettes as a Strategy to Disrupt the Pain-Smoking Reinforcement CycleR21DA052729 · NIDA · DUKE UNIVERSITY · PI SWEITZER, MAGGIE M · 2021 to 2022
$443k
NCATS NIH HHS TL1 TR002555NIDA NIH HHS R21 DA052729
6 · The paper itself

Abstract

Chronic pain affects ∼20% of the adult population and is associated with smoking. Smoking and pain worsen each other in the long term, but short-term temporal associations between smoking and pain throughout the day are unclear. Understanding these relationships may inform strategies for managing comorbid smoking and pain. Participants with chronic back pain who smoke responded to 81.5% of ecological momentary assessment (EMA) prompts delivered 5 times daily. Independent variables were: 1) urge to smoke (from 1-9), 2) intention to smoke (about to smoke, not about to smoke), and 3) smoking recency (smoked <30 min ago, smoked >30 min ago); smoking now was included as a separate category in models 2 and 3. Associations with pain intensity (from 1-9) were estimated using multi-level models, including an interaction term between the independent variable and Pain and Smoking Inventory score (PSI). Urge to smoke was associated with increased pain intensity (β=0.10 [SE=0.02], p<0.001), and this difference was greater for individuals with higher PSI scores (β=0.03 [0.01], p=0.003). Not being about to smoke was associated with lower pain intensity than smoking now (β=-0.29 [0.09], p=0.001). Compared to smoking now, both smoking <30 min ago (β=-0.30 [0.09], p=0.001) and smoking >30 min ago (β=-0.23 [0.11], p=0.029) were associated with lower pain intensity. Smoking urges may increase pain intensity (or vice versa), especially when people perceive strong relationships between smoking and pain. Smoking may also attenuate perceived pain. Further research is needed on interventions that combine tailored smoking cessation treatments and behavioral pain management strategies. PERSPECTIVE: This analysis of momentary data reported throughout the day by people with back pain who smoke revealed novel insights into short-term relationships between pain and smoking. Study results can inform future treatment development for individuals with chronic pain who smoke.

Indexed as

Back PainChronic PainCigarette SmokingEcological Momentary AssessmentAdultFemaleHumansMaleMiddle AgedPain MeasurementBack painChronic painEcological momentary assessmentSmokingTobacco

Identifiers

PMID39765280
PMCPMC11893238

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.