Evidence map›Paper›PMID 39765226›Full record

ArticleCurrent biology : CB2025

Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits.

Suzanne O Nolan, Patrick R Melugin, Kirsty R Erickson, Wilson R Adams, Zahra Z Farahbakhsh, Colleen E Mcgonigle, Michelle H Kwon, Vincent D Costa, Troy A Hackett, Verginia C Cuzon Carlson and 4 more

Abstract read
In one paragraph

Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Suzanne O NolanDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA.
Patrick R MeluginDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA.
Kirsty R EricksonDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA.
Wilson R AdamsDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA.
Zahra Z FarahbakhshDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA.
Colleen E McgonigleDepartment of Psychology, Indiana University Indianapolis, Indianapolis, IN 46202, USA.
Michelle H KwonDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA.
Vincent D CostaDivision of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA; Division of Developmental and Cognitive Neuroscience, Emory National Primate Research Center, Atlanta, GA 30329, USA.
Troy A HackettDepartment of Hearing and Speech Sciences, Department of Psychology, Vanderbilt University School of Medicine, Vanderbilt University, Nashville, TN 37232, USA.
Verginia C Cuzon CarlsonDivision of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA.
Christos ConstantinidisDepartment of Biomedical Engineering, Department of Pharmacology, Vanderbilt University, Nashville, TN 37235, USA.
Christopher C LapishDepartment of Anatomy, Cell Biology, & Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Kathleen A GrantDivision of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA. Electronic address: grantka@ohsu.edu.
Cody A SicilianoDepartment of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA; Department of Anatomy, Cell Biology, & Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address: cody.siciliano@vanderbilt.edu.

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Translational measures of risk for excessive alcohol consumptionP60AA010760 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI TAMARA J. PHILLIPS · 2006 to 2026
$34.5M
Stress and Ethanol Self-Administration in MonkeysU01AA013510 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KATHLEEN A GRANT · 2002 to 2026
$11.8M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Monkey Alcohol Tissue Research Resource (MATRR)R24AA019431 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Mary Lauren Benton, Verginia Carmella Cuzon Carlson · 2010 to 2026
$10.3M
Program in NeurogenomicsT32MH065215 · NIMH · VANDERBILT UNIVERSITY · PI ROGER J COLBRAN · 2002 to 2026
$6.4M
INIA: Stress, Anxiety and Excessive Alcohol Drinking (Administrative Core)U24AA013641 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KATHLEEN A GRANT · 2016 to 2026
$3.4M
Mesocortical neuromodulation in punishment-resistant alcohol drinkingR01AA030115 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.1M
8/8: INIA Stress and Chronic Alcohol Interactions: Cross-species plasticity signatures of alcohol and stressU01AA029971 · NIAAA · VANDERBILT UNIVERSITY · PI Cody Siciliano · 2022 to 2026
$2.0M
Defining the role of cortical circuit dynamics in learning and addictionR00DA045103 · NIDA · VANDERBILT UNIVERSITY · PI SICILIANO, CODY · 2020 to 2022
$764k
Estrogen receptor regulation of cocaine effects on dopamine terminalsF31DA056202 · NIDA · VANDERBILT UNIVERSITY · PI ERICKSON, KIRSTY R. · 2022 to 2025
$149k
Defining the role of compartment-specific dopamine dynamics in reinforcement learningF32DA051136 · NIDA · VANDERBILT UNIVERSITY · PI NOLAN, SUZANNE OLIVIA · 2020 to 2022
$136k
NIAAA NIH HHS F31 AA029626NIAAA NIH HHS P60 AA010760NIAAA NIH HHS R01 AA030115NIAAA NIH HHS R24 AA019431NIAAA NIH HHS U01 AA013510NIAAA NIH HHS U01 AA029971NIAAA NIH HHS U24 AA013641NICHD NIH HHS P50 HD103537NIDA NIH HHS F31 DA056196NIDA NIH HHS F31 DA056202NIDA NIH HHS F32 DA051136NIDA NIH HHS R00 DA045103NIH HHS P51 OD011092NIMH NIH HHS T32 MH065215
6 · The paper itself

Abstract

Human and non-human primate studies clearly implicate the dorsolateral prefrontal cortex (dlPFC) as critical for advanced cognitive functions.

Indexed as

Dorsolateral Prefrontal CortexMacaca mulattaNerve NetPrefrontal CortexAnimalsCognitionMalecalcium imagingcognitive flexibilitycortical excitabilitydorsolateral prefrontal cortexindividual differencesneural population codingneuronal ensemble dynamicspersistent activityrecurrent networksrhesus macaque

Identifiers

PMID39765226
PMCPMC11832050

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.