Evidence map›Paper›PMID 39764647›Full record

ArticleCNS neuroscience & therapeutics2025

Association Between Coffee Intake and Common Mental Disorders: Insights From Genetic Analysis.

Zhiqiang Du, Ying Jiang, Yuan Shen, Qin Zhou, Peng Gong, Haohao Zhu

Abstract readLetter
In one paragraph

Article in CNS neuroscience & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiqiang DuAffiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.
Ying JiangAffiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.
Yuan ShenAffiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.
Qin ZhouAffiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.
Peng GongAffiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.
Haohao ZhuAffiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, China.ORCID 0000-0001-8897-0279

Funding

the Medical Key Discipline Program of the Wuxi Health Commission FZXK2021012the Scientific Research Program of the Wuxi Health Commission Q202101the Scientific Research Program of the Wuxi Health Commission ZH202110the Top Talent Support Program for young and middle-aged people of the Wuxi Health Committee HB2023088the Wuxi Municipal Bureau of Science and Technology K20231039the Wuxi Municipal Bureau of Science and Technology K20231049Wuxi Taihu Talent Project WXTTP2021
6 · The paper itself

Abstract

The study found a significant causal relationship between coffee intake and obsessive-compulsive disorder, showing a negative correlation. There was no causal relationship between coffee intake and other mental disorders. The sensitivity analysis test found no pleiotropy affecting the results, and no single nucleotide polymorphism had a major impact on the robustness of the results, indicating that the results are stable and reliable.

Indexed as

CoffeeMental DisordersPolymorphism, Single NucleotideAdultFemaleHumansMaleObsessive-Compulsive DisorderCoffeeCoffee intakeMendelian randomizationMental disordersObsessive‐compulsive disorder

Identifiers

PMID39764647
PMCPMC11705407

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.