Evidence map›Paper›PMID 39764602›Full record

ArticleEnvironmental science & technology2025

Guarding Drinking Water Safety against Harmful Algal Blooms: Could UV/Cl

Minghao Kong, Evangelia Anna Passa, Toby Sanan, Afzaal Nadeem Mohammed, Alexandria L B Forster, Patrick T Justen, Armah de la Cruz, Judy A Westrick, Kevin O'Shea, Bangxing Ren and 5 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Minghao KongEnvironmental Engineering and Science, Department of Chemical and Environmental Engineering (ChEE), University of Cincinnati, Cincinnati, Ohio 45221, United States.ORCID 0000-0002-8591-9088
Evangelia Anna PassaEnvironmental Engineering and Science, Department of Chemical and Environmental Engineering (ChEE), University of Cincinnati, Cincinnati, Ohio 45221, United States.
Toby SananOffice of Research and Development, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, United States.
Afzaal Nadeem MohammedMolecular Toxicology Division, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, United States.
Alexandria L B ForsterDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208, United States.ORCID 0000-0002-4680-1335
Patrick T JustenDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208, United States.ORCID 0009-0006-2140-5797
Armah de la CruzOffice of Research and Development, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, United States.
Judy A WestrickDepartment of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.ORCID 0000-0002-1712-5737
Kevin O'SheaDepartment of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.ORCID 0000-0002-9695-4321
Bangxing RenEnvironmental Engineering and Science, Department of Chemical and Environmental Engineering (ChEE), University of Cincinnati, Cincinnati, Ohio 45221, United States.
Mallikarjuna N NadagoudaOffice of Research and Development, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, United States.ORCID 0000-0002-4800-4436
Jagjit S YadavMolecular Toxicology Division, Department of Environmental and Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, United States.ORCID 0000-0001-5036-3609
Xiaodi DuanKey Laboratory of Organic Compound Pollution Control Engineering (MOE), School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.
Susan D RichardsonDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208, United States.ORCID 0000-0001-6207-4513
Dionysios D DionysiouEnvironmental Engineering and Science, Department of Chemical and Environmental Engineering (ChEE), University of Cincinnati, Cincinnati, Ohio 45221, United States.

Funding

Research Experience & Training Coordination CoreP42ES030991 · NIEHS · WAYNE STATE UNIVERSITY · PI Judy A Westrick · 2022 to 2026
$13.9M
Translational Research Support CoreP30ES036084 · NIEHS · WAYNE STATE UNIVERSITY · PI Melissa A Runge-Morris · 2024 to 2026
$5.2M
Synthesis and quantitation of microcystins and anabaenopeptins in the Great Lakes region to establish human exposure risks via ingestion and inhalationR01ES034017 · NIEHS · WAYNE STATE UNIVERSITY · PI Andrew P Ault, Andrew Michael Fribley · 2023 to 2026
$2.3M
NIEHS NIH HHS P30 ES036084NIEHS NIH HHS P42 ES030991NIEHS NIH HHS R01 ES034017
6 · The paper itself

Abstract

Frequent and severe occurrences of harmful algal blooms increasingly threaten human health by the release of microcystins (MCs). Urgent attention is directed toward managing MCs, as evidenced by rising HAB-related do not drink/do not boil advisories due to unsafe MC levels in drinking water. UV/chlorine treatment, in which UV light is applied simultaneously with chlorine, showed early promise for effectively degrading MC-LR to values below the World Health Organization's guideline limits. Still, much is unknown regarding potential disinfection byproduct formation and associated toxicity, which can occur from the reaction of chlorine and other reactive species with MCs and algal and natural organic matter. To ensure UV/chlorine guarding drinking water for human consumption, the degradation and detoxification of four of the most problematic MC variants, namely, MC-LR, -RR, -YR, and -LA, which differ in amino acid substituents, were evaluated using UV/chlorine and compared to results from chlorination. Overall, UV/chlorine effectively enhanced MC degradation kinetics and generated less halogenated disinfection byproducts in the target analysis of 11 types of DBPs_C

Indexed as

Drinking WaterHarmful Algal BloomUltraviolet RaysChlorineDisinfectionHumansMicrocystinsWater PurificationChlorineDrinking WaterMicrocystinscyanotoxinsfreshwater salinizationmolecular chlorineUV/Cl2

Identifiers

PMID39764602
PMCPMC11908621

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.