Evidence map›Paper›PMID 39764494›Full record

ArticleBioscience of microbiota, food and health2025

Verification of an alteration in the gut microbiota that increases nutritional risk in patients on hemodialysis.

Sotaro Fukuhara, Hiromitsu Ohmori, Tomio Matsumoto, Daisuke Takei, Koji Matsuoka, Masahiko Takemoto, Ryo Sumimoto, Hideki Ohdan

Abstract read
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In one paragraph

Article in Bioscience of microbiota, food and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sotaro FukuharaDepartment of Surgery, National Hospital Organization Yanai Medical Center, 95 Ihonosho, Yamaguchi 742-1352, Japan.
Hiromitsu OhmoriDepartment of Pediatrics, National Hospital Organization Yanai Medical Center, 95 Ihonosho, Yamaguchi 742-1352, Japan.
Tomio MatsumotoDepartment of Surgery, National Hospital Organization Yanai Medical Center, 95 Ihonosho, Yamaguchi 742-1352, Japan.
Daisuke TakeiDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
Koji MatsuokaDepartment of Surgery, National Hospital Organization Yanai Medical Center, 95 Ihonosho, Yamaguchi 742-1352, Japan.
Masahiko TakemotoDepartment of Surgery, National Hospital Organization Yanai Medical Center, 95 Ihonosho, Yamaguchi 742-1352, Japan.
Ryo SumimotoDepartment of Surgery, National Hospital Organization Yanai Medical Center, 95 Ihonosho, Yamaguchi 742-1352, Japan.
Hideki OhdanDepartment of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In end-stage kidney disease requiring hemodialysis, patients at nutritional risk have a poor prognosis. The gut microbiota is important for maintaining the nutritional status of patients. However, it remains unclear whether an altered gut microbiota correlates with increased nutritional risk in patients undergoing hemodialysis. Therefore, we retrospectively analyzed patients who underwent hemodialysis at our hospital between April and December 2022. Nutritional risk was evaluated using the Geriatric Nutritional Risk Index (GNRI), and patients were divided into low- and high-GNRI groups. Patients' clinical conditions and alterations in the gut microbiota were compared between the two groups. The study included a total of 38 patients with moderate to severe frailty. The low-GNRI group had 18 patients, and the high-GNRI group had 20 patients. The low-GNRI group had more severely frail patients. Serum transthyretin, cholinesterase, total cholesterol, and β2-microglobulin were significantly lower in the low-GNRI group than in the high-GNRI group. Significant differences in the relative abundances of the Actinobacteria and Proteobacteria phyla were observed between the two groups. The genus

Indexed as

chronic kidney diseasefrailtygut microbiotahemodialysisnutrition

Identifiers

PMID39764494
PMCPMC11700552

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.