Evidence map›Paper›PMID 39764483›Full record

ArticleCommunicative & integrative biology2025

The overlooked role of microbiota-gut-brain communication in child psychiatry: a call for integration in early intervention strategies.

Sunny Cui, Mubtaseem Aronno, Angel K Q Wong, Leah Snodgrass

Abstract read
In one paragraph

Article in Communicative & integrative biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sunny CuiDepartment of Biological Sciences, Dartmouth College, Hanover, NH, USA.ORCID https://orcid.org/0000-0001-5005-3408
Mubtaseem AronnoDepartment of Biological Sciences, Dartmouth College, Hanover, NH, USA.
Angel K Q WongSchulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Leah SnodgrassDepartment of Psychiatry, DeBusk College of Osteopathic Medicine, Harrogate, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging research has highlighted the significant role of microbiota-gut-brain communication in child psychiatric disorders, including autism spectrum disorder (ASD) and anxiety disorders. Despite this, mainstream psychiatric interventions for children continue to focus predominantly on neurological and psychological therapies, neglecting the critical influence of gut microbiota on brain development and behavior. This commentary underscores the need for greater integration of microbiota-targeted therapies, such as dietary interventions, prebiotics, and probiotics, into early psychiatric intervention strategies. By addressing the gut-brain axis as a key component of neurodevelopmental and psychiatric outcomes, clinicians can adopt a more holistic and biologically informed approach to treatment. We propose that future research and clinical practice should prioritize interdisciplinary collaboration to explore how microbiota-based treatments can be incorporated into existing child psychiatry frameworks, offering new avenues for improving long-term mental health outcomes.

Indexed as

Child psychiatrymicrobiota communicationmicrobiota-gut-brain axisneurodevelopmental disordersneuroimmune interactions

Identifiers

PMID39764483
PMCPMC11702936

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.