ArticlePatient preference and adherence2025
Impact of Fasting on Physical Activity Motivation and Weight Reduction in Patients Administered Glucagon-Like Peptide-1 Agonists: A Qualitative Study.
Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Threonic acid, an ascorbic acid metabolite, synergizes with intermittent fasting to ameliorate obesity.Experimental & molecular medicine · 2026Article
- Mental Health, Sleep, and Physical Activity Among Young Saudi Women During Ramadan: A Comparative Cohort Study.Nature and science of sleep · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
Purpose: This study aims to investigate the possible impacts of fasting on physical activity and weight loss in adult users of glucagon-like peptide-1 (GLP-1) agonists, specifically semaglutide and tirzepatide, using qualitative methods to gain in-depth insights into participants' experiences and perceptions. Patients and Methods: A qualitative study was conducted at the Polyclinic at King Faisal University, Al-Ahsa, Saudi Arabia, during and after Ramadan in 2024, along with the completion of International Physical Activity Questionnaires (IPAQs). The semi-structured interviews and the IPAQ were used to assess physical activity levels. A thematic narrative and framework analysis were used to analyze the data, and a descriptive analysis was performed on the IPAQ data. All participants provided their informed consent, and ethical approval was acquired. A total of 14 interviews were conducted. Five refined themes and 3 sub-themes were identified. The findings were presented in accordance with the COREQ (consolidated criteria for reporting qualitative research) guidelines. Results: Ten participants, aged 18-59, were included in the study. Half used semaglutide, four used tirzepatide, and one used both, primarily for blood glucose regulation and weight reduction. The average body mass index (BMI) decreased from 35.246 to 34.155. However, a paired Conclusion: The research indicated that the combination of GLP-1 agonists and physical activity influenced weight loss during fasting in Ramadan among the participants. These findings suggest that combining these medications with increased physical activity and fasting can effectively reduce BMI and improve overall health outcomes for individuals managing weight and chronic diseases over an extended duration.
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