Evidence map›Paper›PMID 39764395›Full record

ArticleArXiv2024

Optical Coherence Elastography Measures Mechanical Tension in the Lens and Capsule

Xu Feng, Guo-Yang Li, Yuxuan Jiang, Owen Shortt-Nguyen, Seok-Hyun Yun

Abstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Xu FengHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Guo-Yang LiHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Yuxuan JiangHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Owen Shortt-NguyenHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Seok-Hyun YunHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.

Funding

In vivo high-resolution mapping of the elastic moduli and tensile stress in the human corneaR01EY034857 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI Seok-Hyun Andy Yun · 2023 to 2026
$2.1M
In vivo optical coherence elastography of the cornea: mapping shear and tensile moduliR01EY033356 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI YUN, SEOK-HYUN ANDY · 2022 to 2024
$1.2M
NEI NIH HHS R01 EY033356NEI NIH HHS R01 EY034857
6 · The paper itself

Abstract

Lens tension is essential for accommodative vision but remains challenging to measure with precision. Here, we present an optical coherence elastography (OCE) technique that quantifies both the tension and elastic modulus of lens tissue and capsule. This method derives mechanical parameters from surface wave dispersion across a critical frequency range of 1-30 kHz. Using isolated lenses from six-month-old pigs, we measured intrinsic anterior capsular tensions of 0-20 kPa and posterior capsular tensions of 40-50 kPa, induced by intra-lenticular pressure at the cortical surface. Young's modulus

Identifiers

PMID39764395
PMCPMC11702812

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.