ReviewInternational journal of vascular medicine2024
Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review.
Review in International journal of vascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bone marrow-derived mesenchymal stem cells combined with intramuscular injection promote the healing of diabetic foot ulcers: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Impact of hyperbaric oxygenation therapy (HBOT) on renal function in human.Scientific reports · 2025Article
- Development and validation of a multi-modality system combining radiomics and deep learning for predicting mid-pregnancy complications and enabling timely pregnancy care.Frontiers in pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia management but also with the management of DM-related complications. Most chronic DM-associated complications are vascular in nature. Thus, hyperbaric oxygen therapy (HBOT) can be used for primary and/or secondary prevention of vascular complications. This systematic review is aimed at providing an up-to-date analysis of the effects of HBOT in patients with diabetic foot ulcers (DFUs) on the prevention of amputation, fitting, and rehabilitation of amputees. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed to conduct this systematic review. PubMed and Web of Science (WOS) database were employed in the search, which ended in November 2023. A risk of bias analysis was performed using the Evidence Project tool. After analyzing the records obtained, 10 studies were identified. However, seven fulfilled the inclusion criteria and were included in this systematic review. All included patients were over 18 years of age and had DM. The degree of DFU was assessed with the Wagner scale, being between 2 and 4, and the age of previous treatment of these DFU was taken into account. The results of the current systematic review showed that significant improvements can be achieved with HBOT when comparing its effects to those of the control group that followed usual care. Most studies included in the review showed positive results for DFU, amputation prevention, fitting, and rehabilitation of amputees. Therefore, the use of a hyperbaric chamber and standard care, as opposed to standard care alone, is favorable in patients with chronic DFUs. Promising and positive results were achieved for wound healing in DFU and the prevention of amputations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.