Evidence map›Paper›PMID 39764245›Full record

ArticleFrontiers in endocrinology2024

Targeted deletion of the pancreatic β-cell oxytocin receptor and its effects on metabolic regulation and β-cell health.

Armando J Mendez, Angela Szeto, Maria Boulina, Jesica Westwright, Hafsha Rahman, Sarah Abushamma, Riley Schneider, Philip M McCabe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Armando J MendezDiabetes Research Institute, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, United States.
Angela SzetoDepartment of Psychology, University of Miami, Coral Gables, FL, United States.
Maria BoulinaDiabetes Research Institute, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, United States.
Jesica WestwrightDepartment of Psychology, University of Miami, Coral Gables, FL, United States.
Hafsha RahmanDepartment of Psychology, University of Miami, Coral Gables, FL, United States.
Sarah AbushammaDepartment of Psychology, University of Miami, Coral Gables, FL, United States.
Riley SchneiderDepartment of Psychology, University of Miami, Coral Gables, FL, United States.
Philip M McCabeDepartment of Psychology, University of Miami, Coral Gables, FL, United States.

Funding

Social Environment, Sympathetic Nervous System & Atherosclerosis in WHHL RabbitsR01HL116387 · NHLBI · UNIVERSITY OF MIAMI CORAL GABLES · PI MCCABE, PHILIP M · 2013 to 2016
$2.2M
NHLBI NIH HHS R01 HL116387
6 · The paper itself

Abstract

The neuropeptide oxytocin (OXT) and its receptor (OXTR) have been shown to play an important role in glucose metabolism, and pancreatic islets express this ligand and receptor. In the current study, OXTR expression was identified in α-, β-, and δ-cells of the pancreatic islet by

Indexed as

Insulin-Secreting CellsMice, KnockoutOxytocinReceptors, OxytocinAnimalsBlood GlucoseGlucose Tolerance TestInsulinInsulin SecretionMaleMiceMice, Inbred C57BLBlood GlucoseInsulinOXTR protein, mouseOxytocinReceptors, Oxytocincellular protectionglycemic regulationinsulinknockout mouseoxytocinoxytocin receptorpancreatic isletsβ-cells

Identifiers

PMID39764245
PMCPMC11700818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.