ArticleFrontiers in bioengineering and biotechnology2024
Musculoskeletal model predicted paraspinal loading may quick estimate the effect of exercise on spine BMD.
Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Diagnostic Perspectives on the Relationship Between Paraspinal Muscles and Bone Mineral Density: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Coordinated Bone-Muscle Axis Association in South China Carp (Foods (Basel, Switzerland) · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Spine is the most commonly found fracture site due to osteoporosis. Combined exercise including high-impact and resistance exercise shows the potential to improve bone mineral density (BMD) in the spine. However, the mechanical loading introduced by exercise, which is the mechanism of BMD changes, has not been investigated. The purpose of this study is to provide a new insight to investigate the mechanical stimuli of exercise induced bone remodelling. Methods: Ten postmenopausal women with osteopenia who finalized a 6-month combined exercise of high-impact and resistance intervention were included. The changes in BMD were analyzed based on QCT images obtained from pre and post intervention. A modified full-body musculoskeletal model was built to estimate paravertebral muscle force (MF) and intervertebral compression force (ICF) during daily activities (walking and heel drop) and combined exercise including high-impact (jumping) and resistance exercise (pulling elastic bands). Results: The paravertebral MF and ICF during jumping and pulling elastic bands exercise were all significantly greater than walking and heel drop exercise with up to 1.22-8.18 times. Spine BMD remained at the same level with no significant decline observed, especially at L1 (pre 247.95 ± 26.77 mg/cm Conclusion: It has been proved that paravertebral muscle forces and intervertebral compression forces generated by the combined exercise, rather than daily exercise, were the main reasons for the improvement of spine BMD. This study contributes into the understanding of exercise induced spine adaptation as well as a potential in fast prediction to evaluate the effect of physical exercise therapy.
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