Evidence map›Paper›PMID 39764017›Full record

ArticlebioRxiv : the preprint server for biology2024

Predicting Future Development of Stress-Induced Anhedonia From Cortical Dynamics and Facial Expression.

Austin A Coley, Kanha Batra, Jeremy M Delahanty, Laurel R Keyes, Rachelle Pamintuan, Assaf Ramot, Jim Hagemann, Christopher R Lee, Vivian Liu, Harini Adivikolanu and 13 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Austin A ColeyThe Salk Institute for Biological Studies, La Jolla, CA.
Kanha BatraThe Salk Institute for Biological Studies, La Jolla, CA.
Jeremy M DelahantyThe Salk Institute for Biological Studies, La Jolla, CA.
Laurel R KeyesThe Salk Institute for Biological Studies, La Jolla, CA.
Rachelle PamintuanThe Salk Institute for Biological Studies, La Jolla, CA.
Assaf RamotUniversity of California, San Diego, La Jolla, CA.
Jim HagemannVrije Universiteit, Amsterdam Netherlands.
Christopher R LeeThe Salk Institute for Biological Studies, La Jolla, CA.
Vivian LiuThe Salk Institute for Biological Studies, La Jolla, CA.
Harini AdivikolanuThe Salk Institute for Biological Studies, La Jolla, CA.
Jianna CressyThe Salk Institute for Biological Studies, La Jolla, CA.
Caroline JiaThe Salk Institute for Biological Studies, La Jolla, CA.
Francesca MassaThe Salk Institute for Biological Studies, La Jolla, CA.
Deryn LeDukeThe Salk Institute for Biological Studies, La Jolla, CA.
Moumen GabirThe Salk Institute for Biological Studies, La Jolla, CA.
Bra'a DurubehThe Salk Institute for Biological Studies, La Jolla, CA.
Lexe LinderhofThe Salk Institute for Biological Studies, La Jolla, CA.
Reesha PatelThe Salk Institute for Biological Studies, La Jolla, CA.
Romy WichmannThe Salk Institute for Biological Studies, La Jolla, CA.
Hao LiThe Salk Institute for Biological Studies, La Jolla, CA.
Kyle B FischerThe Salk Institute for Biological Studies, La Jolla, CA.
Talmo PereiraThe Salk Institute for Biological Studies, La Jolla, CA.
Kay M TyeThe Salk Institute for Biological Studies, La Jolla, CA.

Funding

Neurosciences Graduate Training ProgramT32NS061847 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Brenda L Bloodgood · 2008 to 2026
$7.7M
Neural Circuit Mechanisms of Social Homeostasis in Individuals and Supraorganismal Social GroupsDP1AT009925 · NCCIH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TYE, KAY MAXINE · 2017 to 2021
$6.4M
Solving the Valence Assignment ProblemR37MH102441 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Kay Maxine Tye · 2021 to 2026
$5.6M
Exploring neural circuit mechanisms of social contact and social isolationR01MH115920 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TYE, KAY MAXINE · 2018 to 2022
$2.4M
PSD-95 deficiency alters glutamatergic synapses during development in the prefrontal cortexK00MH124182 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI COLEY, AUSTIN · 2020 to 2023
$274k
NCCIH NIH HHS DP1 AT009925NIMH NIH HHS K00 MH124182NIMH NIH HHS R01 MH115920NIMH NIH HHS R37 MH102441NINDS NIH HHS T32 NS061847
6 · The paper itself

Abstract

The current state of mental health treatment for individuals diagnosed with major depressive disorder leaves billions of individuals with first-line therapies that are ineffective or burdened with undesirable side effects. One major obstacle is that distinct pathologies may currently be diagnosed as the same disease and prescribed the same treatments. The key to developing antidepressants with ubiquitous efficacy is to first identify a strategy to differentiate between heterogeneous conditions. Major depression is characterized by hallmark features such as anhedonia and a loss of motivation

Identifiers

PMID39764017
PMCPMC11702711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.