Evidence map›Paper›PMID 39763933›Full record

ArticlebioRxiv : the preprint server for biology2024

Suppression of meiotic crossovers in pericentromeric heterochromatin requires synaptonemal complex and meiotic recombination factors in

Nila M Pazhayam, Sasha Sagar, Jeff Sekelsky

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Nila M PazhayamCurriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0003-4831-0289
Sasha SagarDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.
Jeff SekelskyCurriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.ORCID 0000-0002-4424-677X

Funding

Mechanisms of Meiotic and Mitotic RecombinationR35GM118127 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JEFF J. SEKELSKY · 2016 to 2026
$6.0M
NRSA in GeneticsT32GM135128 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Daniel J McKay, JEFF J. SEKELSKY · 2020 to 2026
$5.1M
Preventing Age-Associated Oocyte Aneuploidy: Mechanisms Behind the Drosophila melanogaster Centromere EffectF31AG079626 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PAZHAYAM, NILA MADASSARY · 2022 to 2024
$118k
NIA NIH HHS F31 AG079626NIGMS NIH HHS R35 GM118127NIGMS NIH HHS T32 GM135128
6 · The paper itself

Abstract

The centromere effect (CE) is a meiotic phenomenon that ensures meiotic crossover suppression in pericentromeric regions. Despite being a critical safeguard against nondisjunction, the mechanisms behind the CE remain unknown. Previous studies have shown that various regions of the

Identifiers

PMID39763933
PMCPMC11702629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.