Evidence map›Paper›PMID 39763930›Full record

ArticlebioRxiv : the preprint server for biology2024

Cell type transcriptional identities are maintained in cultured

J P McGinnis, Joshua Ortiz-Guzman, Sai Mallannagari, Maria Camila Guevara, Benjamin D W Belfort, Suyang Bao, Snigdha Srivastava, Maria Morkas, Emily Ji, Kalman A Katlowitz and 20 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors.

J P McGinnisDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0009-0003-5669-5913
Joshua Ortiz-GuzmanDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.ORCID 0000-0002-7000-394X
Sai MallannagariDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.
Maria Camila GuevaraDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.
Benjamin D W BelfortDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.ORCID 0000-0002-2866-5763
Suyang BaoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.ORCID 0000-0002-0435-5322
Snigdha SrivastavaDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.
Maria MorkasDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.
Emily JiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.
Kalman A KatlowitzDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-5568-6343
Angela AddisonDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.ORCID 0000-0002-4125-1792
Evelyne K TantryDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.ORCID 0000-0002-1782-0692
Melissa M BlessingDepartment of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-4014-4426
Carrie A MohilaDepartment of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Nisha GadgilDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0009-0008-0215-0703
Samuel G McClugageDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
David F BauerDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-3548-0887
William E WhiteheadDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Guillermo AldaveDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-8286-5830
Omar TanweerDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Naser JaleelDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Ali JalaliDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Akash J PatelDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Sameer A ShethDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-8770-8965
Howard L WeinerDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Shankar GopinathDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-5631-1364
Ganesh RaoDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Akdes Serin HarmanciDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-6374-9041
Daniel CurryDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.
Benjamin R ArenkielDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX,77030, USA.ORCID 0000-0001-9047-2420

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9M
Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Sandesh Chakravarthy Sreenath Nagamani, David Loren Nelson · 2020 to 2026
$9.9M
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
Single Cell Spatial Transcriptomics Shared Instrument at the BCM Core FacilityS10OD032189 · OD · BAYLOR COLLEGE OF MEDICINE · PI CHEN, RUI · 2022 to 2022
$304k
Tecan EVO GenePaint robotS10OD016167 · OD · BAYLOR COLLEGE OF MEDICINE · PI LJUNGBERG, CECILIA · 2013 to 2013
$215k
NCI NIH HHS P30 CA125123NCRR NIH HHS S10 RR024574NICHD NIH HHS P50 HD103555NIH HHS S10 OD016167NIH HHS S10 OD032189
6 · The paper itself

Abstract

It is becoming more broadly accepted that human-based models are needed to better understand the complexities of the human nervous system and its diseases. The recently developed human brain organotypic culture model is one highly promising model that requires the involvement of neurosurgeons and neurosurgical patients. Studies have investigated the electrophysiological properties of neurons in such

Indexed as

brain model developmentepilepsyglioblastomaHuman brainhuman brain organotypic slice culturemedulloblastoma

Identifiers

PMID39763930
PMCPMC11702615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.