Evidence map›Paper›PMID 39763842›Full record

ArticlebioRxiv : the preprint server for biology2024

Inferring fine-scale mutation and recombination rate maps in aye-ayes (

Vivak Soni, Cyril J Versoza, John W Terbot, Jeffrey D Jensen, Susanne P Pfeifer

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Vivak Soni
Cyril J Versoza
John W Terbot
Susanne P PfeiferORCID 0000-0003-1378-2913

Funding

On differentiating selective and neutral evolutionary processesR35GM139383 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI JENSEN, JEFFREY D · 2021 to 2025
$3.0M
Characterizing the full spectrum of genomic variation in biomedically-relevant primatesR35GM151008 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Susanne P Pfeifer · 2023 to 2026
$1.6M
NIGMS NIH HHS R35 GM139383NIGMS NIH HHS R35 GM151008
6 · The paper itself

Abstract

The rate of input of new genetic mutations, and the rate at which that variation is reshuffled, are key evolutionary processes shaping genomic diversity. Importantly, these rates vary not just across populations and species, but also across individual genomes. Despite previous studies having demonstrated that failing to account for rate heterogeneity across the genome can bias the inference of both selective and neutral population genetic processes, mutation and recombination rate maps have to date only been generated for a relatively small number of organisms. Here, we infer such fine-scale maps for the aye-aye (

Identifiers

PMID39763842
PMCPMC11703150

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.