Evidence map›Paper›PMID 39763826›Full record

ArticlebioRxiv : the preprint server for biology2024

The B-type cyclin Clb4 prevents meiosis I sister centromere separation in budding yeast.

Gal Lumbroso, Gisela Cairo, Soni Lacefield, Andrew W Murray

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gal LumbrosoDepartment of Molecular and Cellular Biology, Harvard University, Cambridge MA, USA.ORCID 0009-0000-9259-953X
Gisela CairoDepartment of Biochemistry and Cell Biology, the Geisel School of Medicine at Dartmouth, Hanover NH, USA.ORCID 0000-0002-0221-3689
Soni LacefieldDepartment of Biochemistry and Cell Biology, the Geisel School of Medicine at Dartmouth, Hanover NH, USA.ORCID 0000-0002-2862-5067
Andrew W MurrayDepartment of Molecular and Cellular Biology, Harvard University, Cambridge MA, USA.ORCID 0000-0002-0868-6604

Funding

Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
FEEDBACK CONTROL OF THE CELL CYCLER01GM043987 · NIGMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MURRAY, ANDREW W · 1990 to 2023
$6.4M
FEEDBACK CONTROL OF THE CELL CYCLER37GM043987 · NIGMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI MURRAY, ANDREW W · 1999 to 2009
$4.5M
NIGMS NIH HHS P20 GM113132NIGMS NIH HHS R01 GM043987NIGMS NIH HHS R37 GM043987
6 · The paper itself

Abstract

In meiosis, one round of DNA replication followed by two rounds of chromosome segregation halves the ploidy of the original cell. Accurate chromosome segregation in meiosis I depends on recombination between homologous chromosomes. Sister centromeres attach to the same spindle pole in this division and only segregate in meiosis II. We used budding yeast to select for mutations that produced viable spores in the absence of recombination. The most frequent mutations inactivated

Identifiers

PMID39763826
PMCPMC11702657

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.