Evidence map›Paper›PMID 39763816›Full record

ArticlebioRxiv : the preprint server for biology2024

PPARδ restrains the suppression function of intra-tumoral Tregs by limiting CIITA-MHC II expression.

Qiyuan Yang, Yuqiong Liang, Tomoko Inoue-Hatanaka, Zhiqian Koh, Nadja Ilkenhans, Ethan Suman, Jingting Yu, Ye Zheng

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiyuan YangNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.
Yuqiong LiangNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.
Tomoko Inoue-HatanakaNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.
Zhiqian KohNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.
Nadja IlkenhansNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.
Ethan SumanNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.
Jingting YuRazavi Newman Integrative Genomics and Bioinformatics Core, Salk Institute for Biological Studies, La Jolla, CA, USA.
Ye ZhengNOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA, USA.

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Reuben Shaw · 1985 to 2026
$82.8M
Project 4: Interrogating and harnessing age-related IFN signaling and innate immunity in HCC prevention and therapyP01AG073084 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI PETER D. ADAMS, GERALD SHADEL · 2021 to 2026
$13.6M
San Diego Nathan Shock CenterP30AG068635 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI SHADEL, GERALD · 2020 to 2024
$6.0M
Treg development and function controlled by cis-regulatory circuitsR01AI107027 · NIAID · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ZHENG, YE · 2014 to 2022
$5.0M
High-throughput mapping of selectively vulnerable cell types and projections in aging and Alzheimer's DiseaseRF1AG064049 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI LEE, KUO-FEN, ZADOR, ANTHONY M · 2019 to 2019
$4.7M
Spectral Configured Bigfoot Sorter for Salk Institute Flow Cytometry CoreS10OD034268 · OD · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI O'CONNOR, CAROLYN PEY-MIN · 2023 to 2023
$724k
BD FACSAria Fusion for Flow Cytometry Core FacilityS10OD023689 · OD · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ZHENG, YE · 2018 to 2018
$530k
Define the role of REV-ERB in colonic RORgt+ regulatory T cellsR21AI178938 · NIAID · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ZHENG, YE · 2023 to 2024
$523k
NCI NIH HHS P30 CA014195NIAID NIH HHS R01 AI107027NIAID NIH HHS R21 AI178938NIA NIH HHS P01 AG073084NIA NIH HHS P30 AG068635NIA NIH HHS RF1 AG064049NIH HHS S10 OD023689NIH HHS S10 OD034268
6 · The paper itself

Abstract

Regulatory T cells (T

Identifiers

PMID39763816
PMCPMC11702609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.