Evidence map›Paper›PMID 39763792›Full record

ArticlebioRxiv : the preprint server for biology2024

Nucleosome Spacing Can Fine-Tune Higher Order Chromatin Assembly.

Lifeng Chen, M Julia Maristany, Stephen E Farr, Jinyue Luo, Bryan A Gibson, Lynda K Doolittle, Jorge R Espinosa, Jan Huertas, Sy Redding, Rosana Collepardo-Guevara and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Lifeng ChenDepartment of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-9866-8353
M Julia MaristanyMaxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, UK.ORCID 0009-0009-8875-9225
Stephen E FarrMaxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, UK.ORCID 0000-0003-1438-1265
Jinyue LuoDepartment of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Bryan A GibsonDepartment of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Lynda K DoolittleDepartment of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Jorge R EspinosaYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
Jan HuertasYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.ORCID 0000-0003-2607-5214
Sy ReddingDepartment of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA.ORCID 0000-0003-3463-7985
Rosana Collepardo-GuevaraMaxwell Centre, Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge CB3 0HE, UK.ORCID 0000-0003-1781-7351
Michael K RosenDepartment of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-0775-7917

Funding

Physical determinants of DNA recognition and genome organization in crowded environmentsR35GM147477 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Sy Redding · 2022 to 2026
$2.1M
Cell Organization Through Phase Separation: Mechanisms, Functions and DiseaseR35GM141736 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2021 to 2025
$1.8M
NIGMS NIH HHS R35 GM141736NIGMS NIH HHS R35 GM147477
6 · The paper itself

Abstract

Cellular chromatin displays heterogeneous structure and dynamics, properties that control diverse nuclear processes. Models invoke phase separation of conformational ensembles of chromatin fibers as a mechanism regulating chromatin organization

Identifiers

PMID39763792
PMCPMC11703229

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.